Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.)
Plant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyan...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2022.977292/full |
| _version_ | 1798020630063349760 |
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| author | Rong Zhang Xin Kang Lili Liu Xiaowen Wang Huijuan Li Jianya Zhu Yongchun Cao Hua Zhu |
| author_facet | Rong Zhang Xin Kang Lili Liu Xiaowen Wang Huijuan Li Jianya Zhu Yongchun Cao Hua Zhu |
| author_sort | Rong Zhang |
| collection | DOAJ |
| description | Plant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyanidins (OPC), chlorogenic acid (CGA), or resveratrol (RES). After an 8-week feeding experiment, blood samples were used to analyze the concentrations of biochemical indices. Gut samples were collected to evaluate microbiota, short chain fatty acid (SCFA) levels, and gene expression. The results indicated that polyphenol administration reduced serum glucose and insulin. Lysozyme activity was enhanced by OPC and CGA, and superoxide dismutase activity was increased by CUR, OPC, and CGA. The gut microbial structure of the RES group was segregated from that of the CON, and the genus Bacteroides was identified as a potential biomarker in the CUR, CGA, and RES groups. Total gut SCFA increased in the CUR, CGA, and RES groups. A strong correlation was observed between Bacteroides and SCFA. In conclusion, dietary polyphenols have distinct anti-inflammatory, anti-oxidant, and anti-hyperglycemic activities that may be closely associated with their microbiota-modulation effects. |
| first_indexed | 2024-04-11T17:00:36Z |
| format | Article |
| id | doaj.art-e0d90c42357c41c691500aec3281477f |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-04-11T17:00:36Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-e0d90c42357c41c691500aec3281477f2022-12-22T04:13:09ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2022-10-011310.3389/fmicb.2022.977292977292Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.)Rong Zhang0Xin Kang1Lili Liu2Xiaowen Wang3Huijuan Li4Jianya Zhu5Yongchun Cao6Hua Zhu7Beijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaAnimal Science and Technology College, Beijing University of Agriculture, Beijing, ChinaBeijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaBeijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaBeijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaBeijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaAnimal Science and Technology College, Beijing University of Agriculture, Beijing, ChinaBeijing Key Laboratory of Fishery Biotechnology, Fisheries Science Institute, Beijing Academy of Agriculture and Forestry Sciences, Beijing, ChinaPlant polyphenol supplementation may improve fish health in aquaculture systems. To assess the potential benefits and function mechanism of plant polyphenols in aquaculture, fish were fed either basal feed (CON) or the basal feed supplemented with 500 mg/kg of curcumin (CUR), oligomeric proanthocyanidins (OPC), chlorogenic acid (CGA), or resveratrol (RES). After an 8-week feeding experiment, blood samples were used to analyze the concentrations of biochemical indices. Gut samples were collected to evaluate microbiota, short chain fatty acid (SCFA) levels, and gene expression. The results indicated that polyphenol administration reduced serum glucose and insulin. Lysozyme activity was enhanced by OPC and CGA, and superoxide dismutase activity was increased by CUR, OPC, and CGA. The gut microbial structure of the RES group was segregated from that of the CON, and the genus Bacteroides was identified as a potential biomarker in the CUR, CGA, and RES groups. Total gut SCFA increased in the CUR, CGA, and RES groups. A strong correlation was observed between Bacteroides and SCFA. In conclusion, dietary polyphenols have distinct anti-inflammatory, anti-oxidant, and anti-hyperglycemic activities that may be closely associated with their microbiota-modulation effects.https://www.frontiersin.org/articles/10.3389/fmicb.2022.977292/fullanti-inflammatoryanti-oxidativeanti-hyperglycemicmicrobiomeornamental fishplant extracts |
| spellingShingle | Rong Zhang Xin Kang Lili Liu Xiaowen Wang Huijuan Li Jianya Zhu Yongchun Cao Hua Zhu Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) Frontiers in Microbiology anti-inflammatory anti-oxidative anti-hyperglycemic microbiome ornamental fish plant extracts |
| title | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
| title_full | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
| title_fullStr | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
| title_full_unstemmed | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
| title_short | Gut microbiota modulation by plant polyphenols in koi carp (Cyprinus carpio L.) |
| title_sort | gut microbiota modulation by plant polyphenols in koi carp cyprinus carpio l |
| topic | anti-inflammatory anti-oxidative anti-hyperglycemic microbiome ornamental fish plant extracts |
| url | https://www.frontiersin.org/articles/10.3389/fmicb.2022.977292/full |
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