Clinical and neuropathological features of ALS/FTD with TIA1 mutations

Clinical and neuropathological features of ALS/FTD with TIA1 mutations

Abstract Mutations in the stress granule protein T-cell restricted intracellular antigen 1 (TIA1) were recently shown to cause amyotrophic lateral sclerosis (ALS) with or without frontotemporal dementia (FTD). Here, we provide detailed clinical and neuropathological descriptions of nine cases with T...

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Bibliographic Details
Main Authors: Veronica Hirsch-Reinshagen, Cyril Pottier, Alexandra M. Nicholson, Matt Baker, Ging-Yuek R. Hsiung, Charles Krieger, Pheth Sengdy, Kevin B. Boylan, Dennis W. Dickson, Marsel Mesulam, Sandra Weintraub, Eileen Bigio, Lorne Zinman, Julia Keith, Ekaterina Rogaeva, Sasha A. Zivkovic, David Lacomis, J. Paul Taylor, Rosa Rademakers, Ian R. A. Mackenzie
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Acta Neuropathologica Communications
Subjects:
Amyotrophic lateral sclerosis
Frontotemporal dementia
Frontotemporal lobar degeneration
T-cell restricted intracellular antigen-1
TDP-43
Online Access:http://link.springer.com/article/10.1186/s40478-017-0493-x

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