Renal fibrosis due to multiple cisplatin treatment is exacerbated by kinin B1 receptor antagonism

Cisplatin is a widely used chemotherapeutic drug, but its side effects are a major limiting factor. Nephrotoxicity occurs in one third of patients undergoing cisplatin treatment. The acute tubular injury caused by cisplatin often leads to a defective repair process, which translates into chronic ren...

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Bibliographic Details
Main Authors: A. Budu, L.C. Freitas-Lima, A.C. de Arruda, M.S. Perilhão, J. Barrera-Chimal, R.C. Araújo, G.R. Estrela
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2021-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2021001200602&tlng=en