Lincomycin toxicity in farm rabbits: report on a severe case
In this study, we describe a case of severe toxicity by lincomycin contamination in feed on a farm housing 1800 rabbit does. The farm used a two-batch system, with parities 24 and 3 d ago, respectively. The rabbits that had consumed the feed developed anorexia 24-48 h later, followed by enteritis-di...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Universitat Politècnica de València
2022-06-01
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| Series: | World Rabbit Science |
| Subjects: | |
| Online Access: | https://polipapers.upv.es/index.php/wrs/article/view/16819 |
| _version_ | 1811326234523598848 |
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| author | Joan Maria Rosell Ricard Garriga Jordina Casas Natàlia Majó Jaume Alomar |
| author_facet | Joan Maria Rosell Ricard Garriga Jordina Casas Natàlia Majó Jaume Alomar |
| author_sort | Joan Maria Rosell |
| collection | DOAJ |
| description | In this study, we describe a case of severe toxicity by lincomycin contamination in feed on a farm housing 1800 rabbit does. The farm used a two-batch system, with parities 24 and 3 d ago, respectively. The rabbits that had consumed the feed developed anorexia 24-48 h later, followed by enteritis-diarrhoea and death. Mortality was >70 % in does, >50 % in 28-day-old kits. None of the 7-day-old kits died from this cause. A total of 125 non-lactating does that had consumed another type of feed from the same supplier were not affected; 10 of them were given the contaminated feed and the same problem occurred. Treatment based on presumptive diagnosis was unsuccessful. Microbiological and histopathological studies identified Clostridium spiroforme, which predominated over coliform bacteria. Toxicology studies requested by the producers verified the existence of 1.6 ppm amoxicillin in the first place; weeks later, further analyses determined 410 ppm lincomycin in doe feed. It also contained the prescribed quantity of 199 ppm tilmicosin. We recommended the stamping-out on the farm. |
| first_indexed | 2024-04-13T14:46:32Z |
| format | Article |
| id | doaj.art-e0decbed8604489d9e329f7c8847a245 |
| institution | Directory Open Access Journal |
| issn | 1257-5011 1989-8886 |
| language | English |
| last_indexed | 2024-04-13T14:46:32Z |
| publishDate | 2022-06-01 |
| publisher | Universitat Politècnica de València |
| record_format | Article |
| series | World Rabbit Science |
| spelling | doaj.art-e0decbed8604489d9e329f7c8847a2452022-12-22T02:42:44ZengUniversitat Politècnica de ValènciaWorld Rabbit Science1257-50111989-88862022-06-0130214715210.4995/wrs.2022.1681913760Lincomycin toxicity in farm rabbits: report on a severe caseJoan Maria Rosell0https://orcid.org/0000-0003-3285-1515Ricard Garriga1https://orcid.org/0000-0001-8546-5920Jordina Casas2Natàlia Majó3https://orcid.org/0000-0003-0189-9751Jaume Alomar4https://orcid.org/0000-0002-7203-0634Cunivet ServiceFederació d’Associacions de Cunicultors de Catalunya (FACC)Federació d’Associacions de Cunicultors de Catalunya (FACC)Universitat Autónoma de BarcelonaUniversitat Autónoma de BarcelonaIn this study, we describe a case of severe toxicity by lincomycin contamination in feed on a farm housing 1800 rabbit does. The farm used a two-batch system, with parities 24 and 3 d ago, respectively. The rabbits that had consumed the feed developed anorexia 24-48 h later, followed by enteritis-diarrhoea and death. Mortality was >70 % in does, >50 % in 28-day-old kits. None of the 7-day-old kits died from this cause. A total of 125 non-lactating does that had consumed another type of feed from the same supplier were not affected; 10 of them were given the contaminated feed and the same problem occurred. Treatment based on presumptive diagnosis was unsuccessful. Microbiological and histopathological studies identified Clostridium spiroforme, which predominated over coliform bacteria. Toxicology studies requested by the producers verified the existence of 1.6 ppm amoxicillin in the first place; weeks later, further analyses determined 410 ppm lincomycin in doe feed. It also contained the prescribed quantity of 199 ppm tilmicosin. We recommended the stamping-out on the farm.https://polipapers.upv.es/index.php/wrs/article/view/16819animal welfareclostridium spiroformelincomycinrabbittoxicosis |
| spellingShingle | Joan Maria Rosell Ricard Garriga Jordina Casas Natàlia Majó Jaume Alomar Lincomycin toxicity in farm rabbits: report on a severe case World Rabbit Science animal welfare clostridium spiroforme lincomycin rabbit toxicosis |
| title | Lincomycin toxicity in farm rabbits: report on a severe case |
| title_full | Lincomycin toxicity in farm rabbits: report on a severe case |
| title_fullStr | Lincomycin toxicity in farm rabbits: report on a severe case |
| title_full_unstemmed | Lincomycin toxicity in farm rabbits: report on a severe case |
| title_short | Lincomycin toxicity in farm rabbits: report on a severe case |
| title_sort | lincomycin toxicity in farm rabbits report on a severe case |
| topic | animal welfare clostridium spiroforme lincomycin rabbit toxicosis |
| url | https://polipapers.upv.es/index.php/wrs/article/view/16819 |
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