The Immunology of Macrophage Activation Syndrome

The Immunology of Macrophage Activation Syndrome

Synonymous with secondary hemophagocytic lymphohistiocytosis, macrophage activation syndrome (MAS) is a term used by rheumatologists to describe a potentially life-threatening complication of systemic inflammatory disorders, most commonly systemic juvenile idiopathic arthritis (sJIA) and systemic lu...

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Bibliographic Details
Main Authors: Courtney B. Crayne, Sabrin Albeituni, Kim E. Nichols, Randy Q. Cron
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
macrophage activation syndrome
hemophagocytic lymphohistiocytosis
cytokine storm
IL-1
IL-6
IL-18
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00119/full

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