Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023
Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagn...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
|
| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/12/6/1054 |
| _version_ | 1827738942513872896 |
|---|---|
| author | Mehmet Kursat Yilmaz Ahmad Abbaszadeh Saad Tarabichi Ibrahim Azboy Javad Parvizi |
| author_facet | Mehmet Kursat Yilmaz Ahmad Abbaszadeh Saad Tarabichi Ibrahim Azboy Javad Parvizi |
| author_sort | Mehmet Kursat Yilmaz |
| collection | DOAJ |
| description | Periprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagnosis of PJI. As a result, the diagnosis of PJI is often challenging. Currently, the 2018 ICM definition of PJI is the only validated diagnostic criteria available. This article will review the importance of serum and synovial biomarkers in the diagnosis of PJI. In addition, it will provide a brief overview of the emerging modalities for the identification of infections in this setting. |
| first_indexed | 2024-03-11T02:51:11Z |
| format | Article |
| id | doaj.art-e0e142df2d024a50b2de802d7fff9cd9 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T02:51:11Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-e0e142df2d024a50b2de802d7fff9cd92023-11-18T09:01:24ZengMDPI AGAntibiotics2079-63822023-06-01126105410.3390/antibiotics12061054Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023Mehmet Kursat Yilmaz0Ahmad Abbaszadeh1Saad Tarabichi2Ibrahim Azboy3Javad Parvizi4Rothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA 19107, USARothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA 19107, USARothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA 19107, USADepartment of Orthopaedics and Traumatology, School of Medicine, Istanbul Medipol University, Istanbul 34810, TurkeyRothman Orthopaedic Institute, Thomas Jefferson University, Philadelphia, PA 19107, USAPeriprosthetic joint infection (PJI) is a rare yet devastating complication following total joint arthroplasty (TJA). Early and accurate diagnosis of PJI is paramount in order to maximize the chances of successful treatment. However, we are yet to identify a single “gold standard” test for the diagnosis of PJI. As a result, the diagnosis of PJI is often challenging. Currently, the 2018 ICM definition of PJI is the only validated diagnostic criteria available. This article will review the importance of serum and synovial biomarkers in the diagnosis of PJI. In addition, it will provide a brief overview of the emerging modalities for the identification of infections in this setting.https://www.mdpi.com/2079-6382/12/6/1054periprosthetic joint infectionserumsynovial fluidmarker |
| spellingShingle | Mehmet Kursat Yilmaz Ahmad Abbaszadeh Saad Tarabichi Ibrahim Azboy Javad Parvizi Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 Antibiotics periprosthetic joint infection serum synovial fluid marker |
| title | Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 |
| title_full | Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 |
| title_fullStr | Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 |
| title_full_unstemmed | Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 |
| title_short | Diagnosis of Periprosthetic Joint Infection: The Utility of Biomarkers in 2023 |
| title_sort | diagnosis of periprosthetic joint infection the utility of biomarkers in 2023 |
| topic | periprosthetic joint infection serum synovial fluid marker |
| url | https://www.mdpi.com/2079-6382/12/6/1054 |
| work_keys_str_mv | AT mehmetkursatyilmaz diagnosisofperiprostheticjointinfectiontheutilityofbiomarkersin2023 AT ahmadabbaszadeh diagnosisofperiprostheticjointinfectiontheutilityofbiomarkersin2023 AT saadtarabichi diagnosisofperiprostheticjointinfectiontheutilityofbiomarkersin2023 AT ibrahimazboy diagnosisofperiprostheticjointinfectiontheutilityofbiomarkersin2023 AT javadparvizi diagnosisofperiprostheticjointinfectiontheutilityofbiomarkersin2023 |