<i>N</i>-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

<i>N</i>-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer

The urokinase plasminogen activator and its receptor (uPA/uPAR) are biomarkers for metastasis, especially in triple-negative breast cancer. We prepared anti-mitotic <i>N</i>-alkylisatin (<i>N</i>-AI)-loaded liposomes functionalized with the uPA/uPAR targeting ligand, plasmino...

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Bibliographic Details
Main Authors: Lisa Belfiore, Darren N. Saunders, Marie Ranson, Kara L. Vine
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pharmaceutics
Subjects:
<i>N</i>-alkylisatin
liposome
urokinase plasminogen activator
PAI-2
SerpinB2
breast cancer
Online Access:https://www.mdpi.com/1999-4923/12/7/641

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