A clinicopathological study of polymorphous light eruption
Background: Polymorphous light eruption (PLE) is the most common idiopathic photodermatoses, with a wide range of clinical presentations that tends to mimic a number of dermatoses. Objective: The aim was to study the clinicopathological profile in patients diagnosed with PLE. Materials and Methods:...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Clinical Dermatology Review |
| Subjects: | |
| Online Access: | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=215;epage=222;aulast=Patil |
| _version_ | 1797649465246482432 |
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| author | Nitin Krishna Patil Aditya Kumar Bubna Maharaja Krishnamoorthy Leena Dennis Joseph |
| author_facet | Nitin Krishna Patil Aditya Kumar Bubna Maharaja Krishnamoorthy Leena Dennis Joseph |
| author_sort | Nitin Krishna Patil |
| collection | DOAJ |
| description | Background: Polymorphous light eruption (PLE) is the most common idiopathic photodermatoses, with a wide range of clinical presentations that tends to mimic a number of dermatoses. Objective: The aim was to study the clinicopathological profile in patients diagnosed with PLE. Materials and Methods: This was a cross-sectional, descriptive study of seventy clinically diagnosed cases of PLE over a period of 1 year, wherein following patient enrolment, they underwent a thorough clinical evaluation, followed by a skin biopsy that was studied categorically. Results: A male preponderance (62.8%) was observed. Majority of patients were in the 21-30 years' age group (28.6%). Pruritus was witnessed in 98.5% of patients. The most common morphological type encountered was plaque PLE (35.7%), followed by lichen nitidus type (11.4%). Commonest site of involvement was sides and back of neck (75.7%), followed by dorsolateral aspect of both arms (31.4%). Hyperkeratosis was identified in 82.8%, spongiosis in 87.1%, liquefactive degeneration of basal cell layer in 82.8%, atrophy in 24.2%, and moderate-to-severe lymphocytic dermal infiltrates in 90% of our cohorts. Conclusion: PLE is a disorder with diverse clinical presentations, manifesting usually in the third decade of life that closely mimics a variety of other cutaneous disorders. Histological examination with certain specific criteria enables the clinician to arrive at a concrete conclusion in those cases where clinical findings alone pose diagnostic difficulties. |
| first_indexed | 2024-03-11T15:46:31Z |
| format | Article |
| id | doaj.art-e0e297cd5e0b4c54a85e1c2d5b207618 |
| institution | Directory Open Access Journal |
| issn | 2542-551X 2542-5528 |
| language | English |
| last_indexed | 2024-03-11T15:46:31Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Clinical Dermatology Review |
| spelling | doaj.art-e0e297cd5e0b4c54a85e1c2d5b2076182023-10-26T06:14:05ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282023-01-017321522210.4103/cdr.cdr_110_21A clinicopathological study of polymorphous light eruptionNitin Krishna PatilAditya Kumar BubnaMaharaja KrishnamoorthyLeena Dennis JosephBackground: Polymorphous light eruption (PLE) is the most common idiopathic photodermatoses, with a wide range of clinical presentations that tends to mimic a number of dermatoses. Objective: The aim was to study the clinicopathological profile in patients diagnosed with PLE. Materials and Methods: This was a cross-sectional, descriptive study of seventy clinically diagnosed cases of PLE over a period of 1 year, wherein following patient enrolment, they underwent a thorough clinical evaluation, followed by a skin biopsy that was studied categorically. Results: A male preponderance (62.8%) was observed. Majority of patients were in the 21-30 years' age group (28.6%). Pruritus was witnessed in 98.5% of patients. The most common morphological type encountered was plaque PLE (35.7%), followed by lichen nitidus type (11.4%). Commonest site of involvement was sides and back of neck (75.7%), followed by dorsolateral aspect of both arms (31.4%). Hyperkeratosis was identified in 82.8%, spongiosis in 87.1%, liquefactive degeneration of basal cell layer in 82.8%, atrophy in 24.2%, and moderate-to-severe lymphocytic dermal infiltrates in 90% of our cohorts. Conclusion: PLE is a disorder with diverse clinical presentations, manifesting usually in the third decade of life that closely mimics a variety of other cutaneous disorders. Histological examination with certain specific criteria enables the clinician to arrive at a concrete conclusion in those cases where clinical findings alone pose diagnostic difficulties.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=215;epage=222;aulast=Patilhistopathologylichen nitidus type of polymorphous light eruptionmicropapular polymorphous light eruptionpolymorphous light eruption |
| spellingShingle | Nitin Krishna Patil Aditya Kumar Bubna Maharaja Krishnamoorthy Leena Dennis Joseph A clinicopathological study of polymorphous light eruption Clinical Dermatology Review histopathology lichen nitidus type of polymorphous light eruption micropapular polymorphous light eruption polymorphous light eruption |
| title | A clinicopathological study of polymorphous light eruption |
| title_full | A clinicopathological study of polymorphous light eruption |
| title_fullStr | A clinicopathological study of polymorphous light eruption |
| title_full_unstemmed | A clinicopathological study of polymorphous light eruption |
| title_short | A clinicopathological study of polymorphous light eruption |
| title_sort | clinicopathological study of polymorphous light eruption |
| topic | histopathology lichen nitidus type of polymorphous light eruption micropapular polymorphous light eruption polymorphous light eruption |
| url | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2023;volume=7;issue=3;spage=215;epage=222;aulast=Patil |
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