Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia
Lime peel contains essential oils are used as anti-oxidants or anti-cancer compounds. As a traditional medicine, lime has been widely used as a substitute for antibiotics. This study aimed to identify active compounds in peel extracts from Citrus aurantifolia that grows in Indonesia. Extraction was...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | Journal of Advanced Pharmaceutical Technology & Research |
| Subjects: | |
| Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=3;spage=107;epage=112;aulast=Asmah |
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| author | Nur Asmah Dewi Fatma Suniarti Anggraini Margono Z Alim Mas'ud Endang Winiati Bachtiar |
| author_facet | Nur Asmah Dewi Fatma Suniarti Anggraini Margono Z Alim Mas'ud Endang Winiati Bachtiar |
| author_sort | Nur Asmah |
| collection | DOAJ |
| description | Lime peel contains essential oils are used as anti-oxidants or anti-cancer compounds. As a traditional medicine, lime has been widely used as a substitute for antibiotics. This study aimed to identify active compounds in peel extracts from Citrus aurantifolia that grows in Indonesia. Extraction was carried out by maceration using three different solvents: ethyl acetate, chloroform, and n-hexane. The extracts were analyzed using gas chromatography-mass spectrometry. The results showed that lime peel contained many important compounds and that 28, 27, and 24 different chemical compounds, both minor and major constituents, were extracted by ethyl acetate, chloroform, and n-hexane, respectively. Four compounds were found in all three solvent extracts, namely, D-limonene, phytol, α-tocopherol, and 5, 7-dimethoxycoumarin. Forty-seven compounds were uniquely present in one solvent, including 17 in ethyl acetate, 17 in chloroform, and 13 in n-hexane. Among the active compounds extracted, several are of biological importance, for example, stigmasterol, D-limonene, Vitamin E, and α-tocopherol. It can be concluded that a variety of distinct compounds are extracted from the same lime peel sample when different solvents are used and that some of these are bioactive compounds with anti-oxidant, anti-microbial, or anti-cancer properties. |
| first_indexed | 2024-12-10T23:55:33Z |
| format | Article |
| id | doaj.art-e0e53907dfa948d4b99c884a548054d2 |
| institution | Directory Open Access Journal |
| issn | 2231-4040 0976-2094 |
| language | English |
| last_indexed | 2024-12-10T23:55:33Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Pharmaceutical Technology & Research |
| spelling | doaj.art-e0e53907dfa948d4b99c884a548054d22022-12-22T01:28:36ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942020-01-0111310711210.4103/japtr.JAPTR_177_19Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, IndonesiaNur AsmahDewi Fatma SuniartiAnggraini MargonoZ Alim Mas'udEndang Winiati BachtiarLime peel contains essential oils are used as anti-oxidants or anti-cancer compounds. As a traditional medicine, lime has been widely used as a substitute for antibiotics. This study aimed to identify active compounds in peel extracts from Citrus aurantifolia that grows in Indonesia. Extraction was carried out by maceration using three different solvents: ethyl acetate, chloroform, and n-hexane. The extracts were analyzed using gas chromatography-mass spectrometry. The results showed that lime peel contained many important compounds and that 28, 27, and 24 different chemical compounds, both minor and major constituents, were extracted by ethyl acetate, chloroform, and n-hexane, respectively. Four compounds were found in all three solvent extracts, namely, D-limonene, phytol, α-tocopherol, and 5, 7-dimethoxycoumarin. Forty-seven compounds were uniquely present in one solvent, including 17 in ethyl acetate, 17 in chloroform, and 13 in n-hexane. Among the active compounds extracted, several are of biological importance, for example, stigmasterol, D-limonene, Vitamin E, and α-tocopherol. It can be concluded that a variety of distinct compounds are extracted from the same lime peel sample when different solvents are used and that some of these are bioactive compounds with anti-oxidant, anti-microbial, or anti-cancer properties.http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=3;spage=107;epage=112;aulast=Asmahanti-microbialbioactive compoundscitrus aurantifoliagas chromatography-ass spectrometrylime peel |
| spellingShingle | Nur Asmah Dewi Fatma Suniarti Anggraini Margono Z Alim Mas'ud Endang Winiati Bachtiar Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia Journal of Advanced Pharmaceutical Technology & Research anti-microbial bioactive compounds citrus aurantifolia gas chromatography-ass spectrometry lime peel |
| title | Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia |
| title_full | Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia |
| title_fullStr | Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia |
| title_full_unstemmed | Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia |
| title_short | Identification of active compounds in ethyl acetate, chloroform, and N-hexane extracts from peels of Citrus aurantifolia from Maribaya, West Java, Indonesia |
| title_sort | identification of active compounds in ethyl acetate chloroform and n hexane extracts from peels of citrus aurantifolia from maribaya west java indonesia |
| topic | anti-microbial bioactive compounds citrus aurantifolia gas chromatography-ass spectrometry lime peel |
| url | http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=3;spage=107;epage=112;aulast=Asmah |
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