Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component
(1) Background: Total Knee Arthroplasty (TKA) in patient with haemophilia (PWH) has usually been performed with the use of cobalt-chrome femoral and titanium tibial components, coupled with standard polyethylene (PE) inserts. The aim of this retrospective study was to evaluate the long-term outcomes...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/12/13/4356 |
| _version_ | 1797591449575882752 |
|---|---|
| author | Christian Carulli Matteo Innocenti Rinaldo Tambasco Alessandro Perrone Roberto Civinini |
| author_facet | Christian Carulli Matteo Innocenti Rinaldo Tambasco Alessandro Perrone Roberto Civinini |
| author_sort | Christian Carulli |
| collection | DOAJ |
| description | (1) Background: Total Knee Arthroplasty (TKA) in patient with haemophilia (PWH) has usually been performed with the use of cobalt-chrome femoral and titanium tibial components, coupled with standard polyethylene (PE) inserts. The aim of this retrospective study was to evaluate the long-term outcomes and survival rates of TKA in a series of consecutive PWH affected by severe knee arthropathy at a single institution. (2) Methods: We followed 65 patients undergoing 91 TKA, implanted using the same implant, characterized by an oxidized zirconium femoral component, coupled with a titanium tibial component, and a highly crosslinked PE. At 1, 6, and 12 months; then every year for 5 years; and finally, every other 3 years, all patients were scored for pain (VAS), function (HJHS; KSS), ROM, and radiographic changes. Kaplan–Meier survivorship curves were used to calculate the implant survival rates. (3) Results: The mean follow-up was 12.3 years (4.2–20.6). All clinical and functional scores improved significantly from preoperatively to the latest follow-up (VAS: from 6.9 to 1.3; HJHS: from 13.4 to 1.9; KSS: from 19.4 to 79; ROM: from 42.4° to 83.6°). The overall survivorship of the implants was 97.5% at the latest follow-up. (4) Conclusions: The present series showed a high survival rate of specific implants potentially linked to the choice of an oxidized zirconium coupled with a highly crosslinked PE. We promote the use of modern implants in these patients in order to ensure long-lasting positive outcomes. |
| first_indexed | 2024-03-11T01:37:36Z |
| format | Article |
| id | doaj.art-e0ea098770154a3ba360c8114775b335 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T01:37:36Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-e0ea098770154a3ba360c8114775b3352023-11-18T16:52:43ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011213435610.3390/jcm12134356Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral ComponentChristian Carulli0Matteo Innocenti1Rinaldo Tambasco2Alessandro Perrone3Roberto Civinini4Orthopaedic Clinic, University of Florence, 50139 Florence, ItalyOrthopaedic Clinic, University of Florence, 50139 Florence, ItalyOrthopaedic Clinic, University of Florence, 50139 Florence, ItalyOrthopaedic Clinic, University of Florence, 50139 Florence, ItalyOrthopaedic Clinic, University of Florence, 50139 Florence, Italy(1) Background: Total Knee Arthroplasty (TKA) in patient with haemophilia (PWH) has usually been performed with the use of cobalt-chrome femoral and titanium tibial components, coupled with standard polyethylene (PE) inserts. The aim of this retrospective study was to evaluate the long-term outcomes and survival rates of TKA in a series of consecutive PWH affected by severe knee arthropathy at a single institution. (2) Methods: We followed 65 patients undergoing 91 TKA, implanted using the same implant, characterized by an oxidized zirconium femoral component, coupled with a titanium tibial component, and a highly crosslinked PE. At 1, 6, and 12 months; then every year for 5 years; and finally, every other 3 years, all patients were scored for pain (VAS), function (HJHS; KSS), ROM, and radiographic changes. Kaplan–Meier survivorship curves were used to calculate the implant survival rates. (3) Results: The mean follow-up was 12.3 years (4.2–20.6). All clinical and functional scores improved significantly from preoperatively to the latest follow-up (VAS: from 6.9 to 1.3; HJHS: from 13.4 to 1.9; KSS: from 19.4 to 79; ROM: from 42.4° to 83.6°). The overall survivorship of the implants was 97.5% at the latest follow-up. (4) Conclusions: The present series showed a high survival rate of specific implants potentially linked to the choice of an oxidized zirconium coupled with a highly crosslinked PE. We promote the use of modern implants in these patients in order to ensure long-lasting positive outcomes.https://www.mdpi.com/2077-0383/12/13/4356haemophiliaknee arthroplastyinhibitorslooseningoxidized zirconiumlong-term results |
| spellingShingle | Christian Carulli Matteo Innocenti Rinaldo Tambasco Alessandro Perrone Roberto Civinini Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component Journal of Clinical Medicine haemophilia knee arthroplasty inhibitors loosening oxidized zirconium long-term results |
| title | Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component |
| title_full | Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component |
| title_fullStr | Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component |
| title_full_unstemmed | Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component |
| title_short | Total Knee Arthroplasty in Haemophilia: Long-Term Results and Survival Rate of a Modern Knee Implant with an Oxidized Zirconium Femoral Component |
| title_sort | total knee arthroplasty in haemophilia long term results and survival rate of a modern knee implant with an oxidized zirconium femoral component |
| topic | haemophilia knee arthroplasty inhibitors loosening oxidized zirconium long-term results |
| url | https://www.mdpi.com/2077-0383/12/13/4356 |
| work_keys_str_mv | AT christiancarulli totalkneearthroplastyinhaemophilialongtermresultsandsurvivalrateofamodernkneeimplantwithanoxidizedzirconiumfemoralcomponent AT matteoinnocenti totalkneearthroplastyinhaemophilialongtermresultsandsurvivalrateofamodernkneeimplantwithanoxidizedzirconiumfemoralcomponent AT rinaldotambasco totalkneearthroplastyinhaemophilialongtermresultsandsurvivalrateofamodernkneeimplantwithanoxidizedzirconiumfemoralcomponent AT alessandroperrone totalkneearthroplastyinhaemophilialongtermresultsandsurvivalrateofamodernkneeimplantwithanoxidizedzirconiumfemoralcomponent AT robertocivinini totalkneearthroplastyinhaemophilialongtermresultsandsurvivalrateofamodernkneeimplantwithanoxidizedzirconiumfemoralcomponent |