The Humanized Mouse Model: What Added Value Does It Offer for HIV Research?
In the early 2000s, novel humanized mouse models based on the transplantation of human hematopoietic stem and progenitor cells (HSPCs) into immunocompromised mice were introduced (hu mice). The human HSPCs gave rise to a lymphoid system of human origin. The HIV research community has greatly benefit...
Main Authors: | Luca Baroncini, Simon Bredl, Kadzioch P. Nicole, Roberto F. Speck |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | Pathogens |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-0817/12/4/608 |
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