Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization?
Abstract Background Haemodialysis is the most frequently prescribed Renal Replacement Therapy modality worldwide. However, patients undergoing this therapy have an unpredictable evolution related to vascular access. Objective To determine the factors associated with the mortality and hospitalization...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Nephrology |
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| Online Access: | https://doi.org/10.1186/s12882-023-03433-6 |
| _version_ | 1827321523806928896 |
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| author | Erwin Campos Miguel Angel Cuevas-Budhart Renata Cedillo-Flores Julián Candelario-López Rigoberto Jiménez Alberto Flores-Almonte Alfonso Ramos-Sanchez Jose C. Divino Filho |
| author_facet | Erwin Campos Miguel Angel Cuevas-Budhart Renata Cedillo-Flores Julián Candelario-López Rigoberto Jiménez Alberto Flores-Almonte Alfonso Ramos-Sanchez Jose C. Divino Filho |
| author_sort | Erwin Campos |
| collection | DOAJ |
| description | Abstract Background Haemodialysis is the most frequently prescribed Renal Replacement Therapy modality worldwide. However, patients undergoing this therapy have an unpredictable evolution related to vascular access. Objective To determine the factors associated with the mortality and hospitalization rate in haemodialysis patients at a third-level care Centre in the Dominican Republic. Methods This was an observational and prospective study involving a cohort of 192 haemodialysis patients. The patient selection was non-probabilistic for convenience, and a direct source questionnaire was applied. Results Of the 192 patients in the cohort, 103 (53.6%) were hospitalized and evaluated. The most frequent cause of hospitalization was catheter-related bloodstream infections (53.4%). Almost one-third (28.2%) of the hospitalized patients died, mostly due to infections (12.6%). Of those who died 29 patients (90%) had a Central venous catheter (CVC) with a non-tunnelled catheter (NTCVC) (65.5%); having an NTC CVC makes a patient 85.5 times more likely to be hospitalized than patients with arteriovenous fistulas. Conclusion Vascular access plays a predominant role in the hospitalization and mortality rates in haemodialysis. Patients with an arteriovenous fistula obtained significantly better outcomes than those with central venous catheters. |
| first_indexed | 2024-04-25T01:08:48Z |
| format | Article |
| id | doaj.art-e0ee91839dee45d2aed93fcc20aab9cf |
| institution | Directory Open Access Journal |
| issn | 1471-2369 |
| language | English |
| last_indexed | 2024-04-25T01:08:48Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Nephrology |
| spelling | doaj.art-e0ee91839dee45d2aed93fcc20aab9cf2024-03-10T12:07:58ZengBMCBMC Nephrology1471-23692024-03-012511510.1186/s12882-023-03433-6Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization?Erwin Campos0Miguel Angel Cuevas-Budhart1Renata Cedillo-Flores2Julián Candelario-López3Rigoberto Jiménez4Alberto Flores-Almonte5Alfonso Ramos-Sanchez6Jose C. Divino Filho7Salvador B. Gautier HospitalMedical Research Unit in Nephrological Diseases of the Mexican Institute of Social SecurityMedical Research Unit in Nephrological Diseases of the Mexican Institute of Social SecurityMedical Research Unit in Nephrological Diseases of the Mexican Institute of Social SecuritySalvador B. Gautier HospitalMedical Center for Diabetes, Obesity and SpecialtiesMacrotech Dominican RepublicDivision of Renal Medicine, CLINTEC, Karolinska InstitutetAbstract Background Haemodialysis is the most frequently prescribed Renal Replacement Therapy modality worldwide. However, patients undergoing this therapy have an unpredictable evolution related to vascular access. Objective To determine the factors associated with the mortality and hospitalization rate in haemodialysis patients at a third-level care Centre in the Dominican Republic. Methods This was an observational and prospective study involving a cohort of 192 haemodialysis patients. The patient selection was non-probabilistic for convenience, and a direct source questionnaire was applied. Results Of the 192 patients in the cohort, 103 (53.6%) were hospitalized and evaluated. The most frequent cause of hospitalization was catheter-related bloodstream infections (53.4%). Almost one-third (28.2%) of the hospitalized patients died, mostly due to infections (12.6%). Of those who died 29 patients (90%) had a Central venous catheter (CVC) with a non-tunnelled catheter (NTCVC) (65.5%); having an NTC CVC makes a patient 85.5 times more likely to be hospitalized than patients with arteriovenous fistulas. Conclusion Vascular access plays a predominant role in the hospitalization and mortality rates in haemodialysis. Patients with an arteriovenous fistula obtained significantly better outcomes than those with central venous catheters.https://doi.org/10.1186/s12882-023-03433-6Chronic Kidney DiseaseHaemodialysisVascular AccessMortality rateHospitalization rateComparison CVC versus AVF |
| spellingShingle | Erwin Campos Miguel Angel Cuevas-Budhart Renata Cedillo-Flores Julián Candelario-López Rigoberto Jiménez Alberto Flores-Almonte Alfonso Ramos-Sanchez Jose C. Divino Filho Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? BMC Nephrology Chronic Kidney Disease Haemodialysis Vascular Access Mortality rate Hospitalization rate Comparison CVC versus AVF |
| title | Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? |
| title_full | Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? |
| title_fullStr | Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? |
| title_full_unstemmed | Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? |
| title_short | Is central venous catheter in haemodialysis still the main factor of mortality after hospitalization? |
| title_sort | is central venous catheter in haemodialysis still the main factor of mortality after hospitalization |
| topic | Chronic Kidney Disease Haemodialysis Vascular Access Mortality rate Hospitalization rate Comparison CVC versus AVF |
| url | https://doi.org/10.1186/s12882-023-03433-6 |
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