De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing

The study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-...

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Main Authors: Eskild Petersen, Faryal Khamis, Giovanni Battista Migliori, Julie Glerup Bay, Ben Marais, Christian Wejse, Alimuddin Zumla
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:International Journal of Infectious Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971217300322
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author Eskild Petersen
Faryal Khamis
Giovanni Battista Migliori
Julie Glerup Bay
Ben Marais
Christian Wejse
Alimuddin Zumla
author_facet Eskild Petersen
Faryal Khamis
Giovanni Battista Migliori
Julie Glerup Bay
Ben Marais
Christian Wejse
Alimuddin Zumla
author_sort Eskild Petersen
collection DOAJ
description The study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-pressure isolation and de-isolation patients from either single rooms or isolation at home is needed. Studies show that the time of effective treatment is the key parameter to follow to determine if patients are contagious to others or not. This means that standard treatment of multi-drug resistant, MDR, TB will not result in the patient being non-infectious. Thus it is important right from the time of diagnosis to know if the patient is infected with MDR TB or not. Thus the early use of molecular techniques to reveal drug susceptibility is important. Clear guidelines stating if patient with microscopy negative sputum no matter infected with fully susceptible or MDR TB, no matter HIV positive or not is needed.
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spelling doaj.art-e0f6b766c32a45428057a14e3b1b9d292022-12-22T00:31:22ZengElsevierInternational Journal of Infectious Diseases1201-97121878-35112017-03-0156C343810.1016/j.ijid.2017.01.029De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missingEskild Petersen0Faryal Khamis1Giovanni Battista Migliori2Julie Glerup Bay3Ben Marais4Christian Wejse5Alimuddin Zumla6Institute of Clinical Medicine, University of Aarhus, DenmarkDepartment of Infectious Diseases, The Royal Hospital, Muscat, OmanWHO Collaborating Centre for TB and Lung Diseases, Maugeri Care and Research Institute Tradate, ItalyDepartment of Infectious Diseases, Aarhus University Hospital, DenmarkThe Children’s Hospital at Westmead and Centre for Research Excellence in Tuberculosis (TB-CRE), Marie Bashir Institute for Infectious Diseases and Biosecurity (MBI), University of Sydney, AustraliaDepartment of Infectious Diseases, Aarhus University Hospital, DenmarkCenter for Clinical Microbiology, Division of Infection and Immunity, University College London, and the National Institute of Health Research Biomedical Research Centre at UCLHospitals, London, United KingdomThe study review guidelines on isolation of patients with tuberculosis, TB, from the World Health Organization, WHO, Centers for Disease Control and Prevention, CDC, and the European Center for Disease Control, ECDC. The review found that unequivocal guidelines for removing patients out of negative-pressure isolation and de-isolation patients from either single rooms or isolation at home is needed. Studies show that the time of effective treatment is the key parameter to follow to determine if patients are contagious to others or not. This means that standard treatment of multi-drug resistant, MDR, TB will not result in the patient being non-infectious. Thus it is important right from the time of diagnosis to know if the patient is infected with MDR TB or not. Thus the early use of molecular techniques to reveal drug susceptibility is important. Clear guidelines stating if patient with microscopy negative sputum no matter infected with fully susceptible or MDR TB, no matter HIV positive or not is needed.http://www.sciencedirect.com/science/article/pii/S1201971217300322TuberculosisIsolationDe-isolationMolecular diagnosis
spellingShingle Eskild Petersen
Faryal Khamis
Giovanni Battista Migliori
Julie Glerup Bay
Ben Marais
Christian Wejse
Alimuddin Zumla
De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
International Journal of Infectious Diseases
Tuberculosis
Isolation
De-isolation
Molecular diagnosis
title De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
title_full De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
title_fullStr De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
title_full_unstemmed De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
title_short De-isolation of patients with pulmonary tuberculosis after start of treatment — clear, unequivocal guidelines are missing
title_sort de isolation of patients with pulmonary tuberculosis after start of treatment clear unequivocal guidelines are missing
topic Tuberculosis
Isolation
De-isolation
Molecular diagnosis
url http://www.sciencedirect.com/science/article/pii/S1201971217300322
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