Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.

Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.

Carcinogenicity tests predict the tumorigenic potential of various substances in the human body by studying tumor induction in experimental animals. There is a need for studies that explore the use of FVB/N-Trp53em2Hwl/Korl (FVB-Trp53+/-) mice, created by TALEN-mediated gene targeting in Korea, in c...

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Bibliographic Details
Main Authors: Na-Won Kim, Sun-Min Seo, Eun-Seon Yoo, Ah-Reum Kang, Ji-Hun Lee, Jae-Hoon Lee, Byeong-Cheol Kang, Han-Woong Lee, Yang-Kyu Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280214

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