Encapsulation of morin in lipid core/PLGA shell nanoparticles significantly enhances its anti-inflammatory activity and oral bioavailability

Encapsulation of morin in lipid core/PLGA shell nanoparticles significantly enhances its anti-inflammatory activity and oral bioavailability

Morin (3,5,7,2′,4′-pentahydroxyflavone; MR) is a bioactive plant polyphenol whose therapeutic efficacy is hindered by its poor biopharmaceutical properties. The purpose of this study was to develop a nanoparticle (NP) formulation to enhance the bioactivity and oral bioavailability of MR. The nanopre...

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Bibliographic Details
Main Authors: Suhair Sunoqrot, Malak Alkurdi, Abdel Qader Al Bawab, Alaa M. Hammad, Rabab Tayyem, Ali Abu Obeed, Mohammed Abufara
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Saudi Pharmaceutical Journal
Subjects:
Anti-inflammatory
Bioavailability
Morin
Nanoencapsulation
PLGA
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423000920

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