The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients
Background: Cataract is one of the most common age-related vision deteriorations, leading to opacification of the lens and therefore visual impairment as well as blindness. Both cataract extraction and the implantation of blue light filtering lens are believed to improve not only vision but also ove...
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2021-10-01
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| author | Anna Maria Sobczak Bartosz Bohaterewicz Magdalena Fafrowicz Aleksandra Domagalik Ewa Beldzik Halszka Oginska Natalia Golonka Marek Rekas Dominik Bronicki Bożena Romanowska-Dixon Joanna Bolsega-Pacud Waldemar Karwowski Farzad V. Farahani Tadeusz Marek |
| author_facet | Anna Maria Sobczak Bartosz Bohaterewicz Magdalena Fafrowicz Aleksandra Domagalik Ewa Beldzik Halszka Oginska Natalia Golonka Marek Rekas Dominik Bronicki Bożena Romanowska-Dixon Joanna Bolsega-Pacud Waldemar Karwowski Farzad V. Farahani Tadeusz Marek |
| author_sort | Anna Maria Sobczak |
| collection | DOAJ |
| description | Background: Cataract is one of the most common age-related vision deteriorations, leading to opacification of the lens and therefore visual impairment as well as blindness. Both cataract extraction and the implantation of blue light filtering lens are believed to improve not only vision but also overall functioning. Methods: Thirty-four cataract patients were subject to resting-state functional magnetic resonance imaging before and after cataract extraction and intraocular lens implantation (IOL). Global and local graph metrics were calculated in order to investigate the reorganization of functional network architecture associated with alterations in blue light transmittance. Psychomotor vigilance task (PVT) was conducted. Results: Graph theory-based analysis revealed decreased eigenvector centrality after the cataract extraction and IOL replacement in inferior occipital gyrus, superior parietal gyrus and many cerebellum regions as well as increased clustering coefficient in superior and inferior parietal gyrus, middle temporal gyrus and various cerebellum regions. PVT results revealed significant change between experimental sessions as patients responded faster after IOL replacement. Moreover, a few regions were correlated with the difference in blue light transmittance and the time reaction in PVT. Conclusion: Current study revealed substantial functional network architecture reorganization associated with cataract extraction and alteration in blue light transmittance. |
| first_indexed | 2024-03-10T05:40:44Z |
| format | Article |
| id | doaj.art-e105dbaa0b5e49bf9a970ee79464d58e |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T05:40:44Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-e105dbaa0b5e49bf9a970ee79464d58e2023-11-22T22:37:07ZengMDPI AGBrain Sciences2076-34252021-10-011111140010.3390/brainsci11111400The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract PatientsAnna Maria Sobczak0Bartosz Bohaterewicz1Magdalena Fafrowicz2Aleksandra Domagalik3Ewa Beldzik4Halszka Oginska5Natalia Golonka6Marek Rekas7Dominik Bronicki8Bożena Romanowska-Dixon9Joanna Bolsega-Pacud10Waldemar Karwowski11Farzad V. Farahani12Tadeusz Marek13Department of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandDepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandDepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandMalopolska Centre of Biotechnology, Jagiellonian University, 30-387 Kraków, PolandDepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandDepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandDepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandOphthalmology Department, Military Institute of Medicine, 04-349 Warsaw, PolandOphthalmology Department, Military Institute of Medicine, 04-349 Warsaw, PolandDepartment of Ophthalmology and Ocular Oncology, Medical College, Jagiellonian University, 31-008 Kraków, PolandDepartment of Ophthalmology and Ocular Oncology, Medical College, Jagiellonian University, 31-008 Kraków, PolandComputational Neuroergonomics Laboratory, Department of Industrial Engineering & Management Systems, University of Central Florida, Orlando, FL 32816, USAComputational Neuroergonomics Laboratory, Department of Industrial Engineering & Management Systems, University of Central Florida, Orlando, FL 32816, USADepartment of Cognitive Neuroscience and Neuroergonomics, Institute of Applied Psychology, Jagiellonian University, 30-348 Kraków, PolandBackground: Cataract is one of the most common age-related vision deteriorations, leading to opacification of the lens and therefore visual impairment as well as blindness. Both cataract extraction and the implantation of blue light filtering lens are believed to improve not only vision but also overall functioning. Methods: Thirty-four cataract patients were subject to resting-state functional magnetic resonance imaging before and after cataract extraction and intraocular lens implantation (IOL). Global and local graph metrics were calculated in order to investigate the reorganization of functional network architecture associated with alterations in blue light transmittance. Psychomotor vigilance task (PVT) was conducted. Results: Graph theory-based analysis revealed decreased eigenvector centrality after the cataract extraction and IOL replacement in inferior occipital gyrus, superior parietal gyrus and many cerebellum regions as well as increased clustering coefficient in superior and inferior parietal gyrus, middle temporal gyrus and various cerebellum regions. PVT results revealed significant change between experimental sessions as patients responded faster after IOL replacement. Moreover, a few regions were correlated with the difference in blue light transmittance and the time reaction in PVT. Conclusion: Current study revealed substantial functional network architecture reorganization associated with cataract extraction and alteration in blue light transmittance.https://www.mdpi.com/2076-3425/11/11/1400neuroimagingfMRIgraphscataractblue light |
| spellingShingle | Anna Maria Sobczak Bartosz Bohaterewicz Magdalena Fafrowicz Aleksandra Domagalik Ewa Beldzik Halszka Oginska Natalia Golonka Marek Rekas Dominik Bronicki Bożena Romanowska-Dixon Joanna Bolsega-Pacud Waldemar Karwowski Farzad V. Farahani Tadeusz Marek The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients Brain Sciences neuroimaging fMRI graphs cataract blue light |
| title | The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients |
| title_full | The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients |
| title_fullStr | The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients |
| title_full_unstemmed | The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients |
| title_short | The Influence of Intraocular Lens Implantation and Alterations in Blue Light Transmittance Level on the Brain Functional Network Architecture Reorganization in Cataract Patients |
| title_sort | influence of intraocular lens implantation and alterations in blue light transmittance level on the brain functional network architecture reorganization in cataract patients |
| topic | neuroimaging fMRI graphs cataract blue light |
| url | https://www.mdpi.com/2076-3425/11/11/1400 |
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