Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds

The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.

Bibliographic Details
Main Authors: Takashi Yamazaki, Yoh Nakajima, Minato Iida, Tomoko Kawasaki-Takasuka
Format: Article
Language:English
Published: Beilstein-Institut 2021-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.17.14
_version_ 1818389134547353600
author Takashi Yamazaki
Yoh Nakajima
Minato Iida
Tomoko Kawasaki-Takasuka
author_facet Takashi Yamazaki
Yoh Nakajima
Minato Iida
Tomoko Kawasaki-Takasuka
author_sort Takashi Yamazaki
collection DOAJ
description The concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.
first_indexed 2024-12-14T04:36:54Z
format Article
id doaj.art-e108e9f6da2b48fb85fc45648de91811
institution Directory Open Access Journal
issn 1860-5397
language English
last_indexed 2024-12-14T04:36:54Z
publishDate 2021-01-01
publisher Beilstein-Institut
record_format Article
series Beilstein Journal of Organic Chemistry
spelling doaj.art-e108e9f6da2b48fb85fc45648de918112022-12-21T23:16:56ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972021-01-0117113213810.3762/bjoc.17.141860-5397-17-14Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compoundsTakashi Yamazaki0Yoh Nakajima1Minato Iida2Tomoko Kawasaki-Takasuka3Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, JapanDivision of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, JapanDivision of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, JapanDivision of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, JapanThe concise preparation of 4,4,4-trifluorobut-2-yn-1-ones by the oxidation of the readily accessible corresponding propargylic alcohols as well as their utilization as Michael acceptors for the construction of aromatic and heteroaromatic compounds are reported.https://doi.org/10.3762/bjoc.17.14cf3-containing propargylic alcoholscf3-containing ynonesoxidationpyrimidinessalicylate derivatives
spellingShingle Takashi Yamazaki
Yoh Nakajima
Minato Iida
Tomoko Kawasaki-Takasuka
Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
Beilstein Journal of Organic Chemistry
cf3-containing propargylic alcohols
cf3-containing ynones
oxidation
pyrimidines
salicylate derivatives
title Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
title_full Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
title_fullStr Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
title_full_unstemmed Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
title_short Facile preparation and conversion of 4,4,4-trifluorobut-2-yn-1-ones to aromatic and heteroaromatic compounds
title_sort facile preparation and conversion of 4 4 4 trifluorobut 2 yn 1 ones to aromatic and heteroaromatic compounds
topic cf3-containing propargylic alcohols
cf3-containing ynones
oxidation
pyrimidines
salicylate derivatives
url https://doi.org/10.3762/bjoc.17.14
work_keys_str_mv AT takashiyamazaki facilepreparationandconversionof444trifluorobut2yn1onestoaromaticandheteroaromaticcompounds
AT yohnakajima facilepreparationandconversionof444trifluorobut2yn1onestoaromaticandheteroaromaticcompounds
AT minatoiida facilepreparationandconversionof444trifluorobut2yn1onestoaromaticandheteroaromaticcompounds
AT tomokokawasakitakasuka facilepreparationandconversionof444trifluorobut2yn1onestoaromaticandheteroaromaticcompounds