Design and synthesis of multivalent α-1,2-trimannose-linked bioerodible microparticles for applications in immune response studies of Leishmania major infection

Design and synthesis of multivalent α-1,2-trimannose-linked bioerodible microparticles for applications in immune response studies of Leishmania major infection

Leishmaniasis, a neglected tropical disease, currently infects approximately 12 million people worldwide with 1 to 2 million new cases each year in predominately underdeveloped countries. The treatment of the disease is severely underdeveloped due to the ability of the Leishmania pathogen to evade a...

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Bibliographic Details
Main Authors: Chelsea L. Rintelmann, Tara Grinnage-Pulley, Kathleen Ross, Daniel E. K. Kabotso, Angela Toepp, Anne Cowell, Christine Petersen, Balaji Narasimhan, Nicola Pohl
Format: Article
Language:English
Published: Beilstein-Institut 2019-03-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
adjuvant
carbohydrates
L. major
microparticle
PAMP
Online Access:https://doi.org/10.3762/bjoc.15.58

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