Decoding the prognostic significance of integrator complex subunit 9 (INTS9) in glioma: links to TP53 mutations, E2F signaling, and inflammatory microenvironments

Decoding the prognostic significance of integrator complex subunit 9 (INTS9) in glioma: links to TP53 mutations, E2F signaling, and inflammatory microenvironments

Abstract Introduction Gliomas, a type of brain neoplasm, are prevalent and often fatal. Molecular diagnostics have improved understanding, but treatment options are limited. This study investigates the role of INTS9 in processing small nuclear RNA (snRNA), which is crucial to generating mature messe...

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Bibliographic Details
Main Authors: Yu-Chieh Lin, Pei-Chi Chang, Dueng-Yuan Hueng, Shih-Ming Huang, Yao-Feng Li
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Cancer Cell International
Subjects:
INTS9
Glioblastoma
Glioma
TCGA
CGGA
GLASS
Online Access:https://doi.org/10.1186/s12935-023-03006-5

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