The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation

Trichoblastoma (TB) is a rare biphasic benign adnexal neoplasm originating from follicular germ cells but clinically, it can simulate basal cell carcinoma (BCC), making the diagnosis more difficult. There are several variants of Trichoblastoma and a good knowledge of these is essential for correct d...

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Main Authors: Gerardo Cazzato, Antonietta Cimmino, Anna Colagrande, Francesca Arezzo, Lucia Lospalluti, Sara Sablone, Teresa Lettini, Leonardo Resta, Giuseppe Ingravallo
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Dermatopathology
Subjects:
Online Access:https://www.mdpi.com/2296-3529/8/3/32
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author Gerardo Cazzato
Antonietta Cimmino
Anna Colagrande
Francesca Arezzo
Lucia Lospalluti
Sara Sablone
Teresa Lettini
Leonardo Resta
Giuseppe Ingravallo
author_facet Gerardo Cazzato
Antonietta Cimmino
Anna Colagrande
Francesca Arezzo
Lucia Lospalluti
Sara Sablone
Teresa Lettini
Leonardo Resta
Giuseppe Ingravallo
author_sort Gerardo Cazzato
collection DOAJ
description Trichoblastoma (TB) is a rare biphasic benign adnexal neoplasm originating from follicular germ cells but clinically, it can simulate basal cell carcinoma (BCC), making the diagnosis more difficult. There are several variants of Trichoblastoma and a good knowledge of these is essential for correct diagnosis and management. We report two new cases observed in the last year at our Pathological Anatomy Operative Unit, and conduct a careful review of the literature, from the first description of this lesion by Headington in 1970 to the most recent classifications.
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spelling doaj.art-e10bf10efeb94fcc867a3a94998853b92023-11-22T12:37:24ZengMDPI AGDermatopathology2296-35292021-07-018326527010.3390/dermatopathology8030032The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case PresentationGerardo Cazzato0Antonietta Cimmino1Anna Colagrande2Francesca Arezzo3Lucia Lospalluti4Sara Sablone5Teresa Lettini6Leonardo Resta7Giuseppe Ingravallo8Section of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Gynecology and Obstetrics, Department of Biomedical Sciences and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Sciences and Oncology (DIMO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Legal Medicine, Department of Interdisciplinary Medicine, Policlinico di Bari Hospital, University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Organ and Emergency Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalyTrichoblastoma (TB) is a rare biphasic benign adnexal neoplasm originating from follicular germ cells but clinically, it can simulate basal cell carcinoma (BCC), making the diagnosis more difficult. There are several variants of Trichoblastoma and a good knowledge of these is essential for correct diagnosis and management. We report two new cases observed in the last year at our Pathological Anatomy Operative Unit, and conduct a careful review of the literature, from the first description of this lesion by Headington in 1970 to the most recent classifications.https://www.mdpi.com/2296-3529/8/3/32trichoblastomaskinadnexal tumorsdermatopathology
spellingShingle Gerardo Cazzato
Antonietta Cimmino
Anna Colagrande
Francesca Arezzo
Lucia Lospalluti
Sara Sablone
Teresa Lettini
Leonardo Resta
Giuseppe Ingravallo
The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
Dermatopathology
trichoblastoma
skin
adnexal tumors
dermatopathology
title The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
title_full The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
title_fullStr The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
title_full_unstemmed The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
title_short The Multiple Faces of Nodular Trichoblastoma: Review of the Literature with Case Presentation
title_sort multiple faces of nodular trichoblastoma review of the literature with case presentation
topic trichoblastoma
skin
adnexal tumors
dermatopathology
url https://www.mdpi.com/2296-3529/8/3/32
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