Circ_0000376 regulates miR-577/HK2/LDHA signaling pathway to promote the growth, invasion and glycolysis of osteosarcoma

Circ_0000376 regulates miR-577/HK2/LDHA signaling pathway to promote the growth, invasion and glycolysis of osteosarcoma

Abstract Background Many studies have confirmed that circular RNAs (circRNAs) mediate the malignant progression of various tumors including osteosarcoma (OS). Our study is to uncover novel molecular mechanisms by which circ_0000376 regulates OS progression. Methods The expression of circ_0000376, mi...

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Bibliographic Details
Main Authors: Hongchun Dai, Guangming Yi, Dong Jiang, Yanmei Min, Zongwei Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteosarcoma
circ_0000376
miR-577
HK2
LDHA
Online Access:https://doi.org/10.1186/s13018-023-04520-y

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