Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years
Purpose: The aim of the study is to correlate between the value of digital rectal examination (DRE), serum prostate-specific antigen (PSA), and transrectal ultrasound (TRUS) as predictors for diagnosing prostate cancer in patients with voiding symptoms. Materials and Methods: A total of 1610 male pa...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Urology Annals |
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| Online Access: | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2019;volume=11;issue=2;spage=135;epage=138;aulast=Alotaibi |
| _version_ | 1819123908335370240 |
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| author | Khalid M Alotaibi |
| author_facet | Khalid M Alotaibi |
| author_sort | Khalid M Alotaibi |
| collection | DOAJ |
| description | Purpose: The aim of the study is to correlate between the value of digital rectal examination (DRE), serum prostate-specific antigen (PSA), and transrectal ultrasound (TRUS) as predictors for diagnosing prostate cancer in patients with voiding symptoms.
Materials and Methods: A total of 1610 male patients seen over a period of 10 years in a single institution had prostate-related voiding problems. Routine studies including DRE and serum PSA were done to all patients. TRUS and TRUS biopsy were performed for patients with suspected prostatic cancer based on abnormal DRE findings and/or serum PSA levels.
Results: TRUS biopsy revealed prostate cancer in 206 out of 1610 patients with prostate-related voiding problems (13%), 40% had abnormal PSA and 28% had abnormal DRE. Combined abnormal PSA and DRE revealed cancer in 63% of patients. This percentage increased to 90% when TRUS was also abnormal, but dropped to 54% when TRUS was normal.
Conclusions: DRE together with serum PSA and TRUS have the highest predictable values for diagnosis of prostate cancer among patients with voiding symptoms. In the absence of abnormal TRUS, PSA and DRE together are more predictable than either alone. Serum PSA alone is more predictable than DRE. Random prostate biopsies should be performed in the presence of high serum PSA, and/or abnormal findings by DRE in male patients with urinary symptoms suggestive of the prostate disease. |
| first_indexed | 2024-12-22T07:15:49Z |
| format | Article |
| id | doaj.art-e11653cce04c44629b2105b947205719 |
| institution | Directory Open Access Journal |
| issn | 0974-7796 0974-7834 |
| language | English |
| last_indexed | 2024-12-22T07:15:49Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Urology Annals |
| spelling | doaj.art-e11653cce04c44629b2105b9472057192022-12-21T18:34:24ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342019-01-0111213513810.4103/UA.UA_151_18Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 yearsKhalid M AlotaibiPurpose: The aim of the study is to correlate between the value of digital rectal examination (DRE), serum prostate-specific antigen (PSA), and transrectal ultrasound (TRUS) as predictors for diagnosing prostate cancer in patients with voiding symptoms. Materials and Methods: A total of 1610 male patients seen over a period of 10 years in a single institution had prostate-related voiding problems. Routine studies including DRE and serum PSA were done to all patients. TRUS and TRUS biopsy were performed for patients with suspected prostatic cancer based on abnormal DRE findings and/or serum PSA levels. Results: TRUS biopsy revealed prostate cancer in 206 out of 1610 patients with prostate-related voiding problems (13%), 40% had abnormal PSA and 28% had abnormal DRE. Combined abnormal PSA and DRE revealed cancer in 63% of patients. This percentage increased to 90% when TRUS was also abnormal, but dropped to 54% when TRUS was normal. Conclusions: DRE together with serum PSA and TRUS have the highest predictable values for diagnosis of prostate cancer among patients with voiding symptoms. In the absence of abnormal TRUS, PSA and DRE together are more predictable than either alone. Serum PSA alone is more predictable than DRE. Random prostate biopsies should be performed in the presence of high serum PSA, and/or abnormal findings by DRE in male patients with urinary symptoms suggestive of the prostate disease.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2019;volume=11;issue=2;spage=135;epage=138;aulast=AlotaibiDigital rectal examinationprostate biopsiesprostate cancerprostatic specific antigentransrectal ultrasoundvoiding symptoms |
| spellingShingle | Khalid M Alotaibi Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years Urology Annals Digital rectal examination prostate biopsies prostate cancer prostatic specific antigen transrectal ultrasound voiding symptoms |
| title | Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years |
| title_full | Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years |
| title_fullStr | Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years |
| title_full_unstemmed | Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years |
| title_short | Incidence of prostate cancer among patients with prostate-related urinary symptoms: A single institution series in 10 years |
| title_sort | incidence of prostate cancer among patients with prostate related urinary symptoms a single institution series in 10 years |
| topic | Digital rectal examination prostate biopsies prostate cancer prostatic specific antigen transrectal ultrasound voiding symptoms |
| url | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2019;volume=11;issue=2;spage=135;epage=138;aulast=Alotaibi |
| work_keys_str_mv | AT khalidmalotaibi incidenceofprostatecanceramongpatientswithprostaterelatedurinarysymptomsasingleinstitutionseriesin10years |