Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological...

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Bibliographic Details
Main Authors: Muthiah Subramanian, M.S. Harikrishnan, Mukund A. Prabhu, Praveen G. Pai, Saritha S. Shekhar, Kumaraswamy Natarajan
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Indian Pacing and Electrophysiology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S0972629217300918
Description
Summary:Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology. Keywords: Familial, AVNRT, Tachycardia
ISSN:0972-6292

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