Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review

Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological...

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Main Authors: Muthiah Subramanian, M.S. Harikrishnan, Mukund A. Prabhu, Praveen G. Pai, Saritha S. Shekhar, Kumaraswamy Natarajan
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Indian Pacing and Electrophysiology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S0972629217300918
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author Muthiah Subramanian
M.S. Harikrishnan
Mukund A. Prabhu
Praveen G. Pai
Saritha S. Shekhar
Kumaraswamy Natarajan
author_facet Muthiah Subramanian
M.S. Harikrishnan
Mukund A. Prabhu
Praveen G. Pai
Saritha S. Shekhar
Kumaraswamy Natarajan
author_sort Muthiah Subramanian
collection DOAJ
description Multiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology. Keywords: Familial, AVNRT, Tachycardia
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spelling doaj.art-e1181473024c4422aad4903cb47a5ae62022-12-22T03:48:35ZengElsevierIndian Pacing and Electrophysiology Journal0972-62922017-11-01176176179Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic reviewMuthiah Subramanian0M.S. Harikrishnan1Mukund A. Prabhu2Praveen G. Pai3Saritha S. Shekhar4Kumaraswamy Natarajan5Corresponding author.; Department of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaDepartment of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaDepartment of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaDepartment of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaDepartment of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaDepartment of Cardiology at Amrita Institute of Medical Sciences, Amrita Lane, Ponekkara, Kochi, Kerala 682041, IndiaMultiple reports of familial clustering suggest that genetic factors may contribute in the pathogenesis of atrioventricular nodal re-entrant tachycardia (AVNRT). We report three cases of AVNRT in a father and his two sons along with a review of literature of other similar cases. Electrophysiological studies induced typical AVNRT, which was successfully eliminated by radiofrequency ablation in all of them. Of the 22 reported cases, 96% had typical (slow-fast) variant of AVNRT. The predominant pattern of inheritance appears to be autosomal dominant, though other patterns may exist. Further research is needed to understand the genetic influence of AVNRT and its pathophysiology. Keywords: Familial, AVNRT, Tachycardiahttp://www.sciencedirect.com/science/article/pii/S0972629217300918
spellingShingle Muthiah Subramanian
M.S. Harikrishnan
Mukund A. Prabhu
Praveen G. Pai
Saritha S. Shekhar
Kumaraswamy Natarajan
Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
Indian Pacing and Electrophysiology Journal
title Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_full Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_fullStr Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_full_unstemmed Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_short Familial atrioventricular nodal re-entrant tachycardia: A case seriers and a systematic review
title_sort familial atrioventricular nodal re entrant tachycardia a case seriers and a systematic review
url http://www.sciencedirect.com/science/article/pii/S0972629217300918
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AT praveengpai familialatrioventricularnodalreentranttachycardiaacaseseriersandasystematicreview
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