Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review

Squamous Cell Papilloma (SCP) is a benign, asymptomatic, exophytic cauliflower-like growth of mucosal mass. It is mostly associated with Human Papilloma Virus (HPV) subtypes 6 and 11, and has a very low virulence and infectivity rate. The papillomas are commonly known as warts or verrucas when fou...

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Main Authors: Ridhima Singhal, Anjali Yadav, Shikha Tewari, Nishi Tanwar, Anju Devi
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2023-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://www.jcdr.net/articles/PDF/18337/64086_CE[Ra1]_F(IS)_QC(AN_OM)_PF1(VD_KM)_PFA(VD_KM)_PN(KM).pdf
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author Ridhima Singhal
Anjali Yadav
Shikha Tewari
Nishi Tanwar
Anju Devi
author_facet Ridhima Singhal
Anjali Yadav
Shikha Tewari
Nishi Tanwar
Anju Devi
author_sort Ridhima Singhal
collection DOAJ
description Squamous Cell Papilloma (SCP) is a benign, asymptomatic, exophytic cauliflower-like growth of mucosal mass. It is mostly associated with Human Papilloma Virus (HPV) subtypes 6 and 11, and has a very low virulence and infectivity rate. The papillomas are commonly known as warts or verrucas when found on the skin. The typical lesion is a single mass with finger-like extensions, resembling a soft, pedunculated growth supported by a stem or stalk. If keratin, a skin protein, accumulates around the lesion, the projections can be long and pointed or short and rounded. Intraorally, the most common sites of occurrence are the tongue, lips, buccal mucosa, palate, and uvula. Hereby, the author present a case report of 25-year-old male patient with a 4x9 mm exophytic growth exhibiting a pebbled surface in the upper left first premolar region, with no signs of radiographic bone loss. Additionally, smaller pinpoint lesions were observed bilaterally in the interdental region of the first and second maxillary molars. A nevus on the right side of the face was also noted. Histological analysis confirmed the diagnosis of SCP. The presence of multifocal gingival squamous papilloma, along with an extraoral nevus, represents a novel finding that warrants reporting. The gingival lesion in the maxillary left first premolar region was surgically excised, along with 1 mm of healthy surrounding gingiva. This resulted in complete healing, and no recurrence was observed during the 12-month follow-up period.
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spelling doaj.art-e11a9249e32247c9822354e010f5459a2023-09-16T09:11:18ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2023-08-011708121510.7860/JCDR/2023/64086.18337Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature ReviewRidhima Singhal0Anjali Yadav1Shikha Tewari2Nishi Tanwar3Anju Devi4Postgraduate Student, Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.Postgraduate Student, Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.Senior Professor, Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.Professor, Department of Periodontics, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.Professor, Department of Oral Pathology, Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.Squamous Cell Papilloma (SCP) is a benign, asymptomatic, exophytic cauliflower-like growth of mucosal mass. It is mostly associated with Human Papilloma Virus (HPV) subtypes 6 and 11, and has a very low virulence and infectivity rate. The papillomas are commonly known as warts or verrucas when found on the skin. The typical lesion is a single mass with finger-like extensions, resembling a soft, pedunculated growth supported by a stem or stalk. If keratin, a skin protein, accumulates around the lesion, the projections can be long and pointed or short and rounded. Intraorally, the most common sites of occurrence are the tongue, lips, buccal mucosa, palate, and uvula. Hereby, the author present a case report of 25-year-old male patient with a 4x9 mm exophytic growth exhibiting a pebbled surface in the upper left first premolar region, with no signs of radiographic bone loss. Additionally, smaller pinpoint lesions were observed bilaterally in the interdental region of the first and second maxillary molars. A nevus on the right side of the face was also noted. Histological analysis confirmed the diagnosis of SCP. The presence of multifocal gingival squamous papilloma, along with an extraoral nevus, represents a novel finding that warrants reporting. The gingival lesion in the maxillary left first premolar region was surgically excised, along with 1 mm of healthy surrounding gingiva. This resulted in complete healing, and no recurrence was observed during the 12-month follow-up period.https://www.jcdr.net/articles/PDF/18337/64086_CE[Ra1]_F(IS)_QC(AN_OM)_PF1(VD_KM)_PFA(VD_KM)_PN(KM).pdfbenign neoplasmhuman papilloma virusoral cavity
spellingShingle Ridhima Singhal
Anjali Yadav
Shikha Tewari
Nishi Tanwar
Anju Devi
Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
Journal of Clinical and Diagnostic Research
benign neoplasm
human papilloma virus
oral cavity
title Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
title_full Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
title_fullStr Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
title_full_unstemmed Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
title_short Multifocal Gingival Squamous Cell Papilloma: A Case Report and Literature Review
title_sort multifocal gingival squamous cell papilloma a case report and literature review
topic benign neoplasm
human papilloma virus
oral cavity
url https://www.jcdr.net/articles/PDF/18337/64086_CE[Ra1]_F(IS)_QC(AN_OM)_PF1(VD_KM)_PFA(VD_KM)_PN(KM).pdf
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