Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment

Hyperglycemia in T2DM is based on three main mechanisms: insulin resistance, progressive β-cell dysfunction, and excess glucose production by the liver.The onset of T2DM is usually preceded by a long period of insulin resistance. Prescribing sugar drugs that affect different links of pathogenesis, r...

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Main Authors: M. V. Shestakova, M. B. Antsiferov, A. S. Ametov, G. R. Galstyan, T. Y. Demidova, A. M. Mkrtumyan, N. A. Petunina
Format: Article
Language:English
Published: Endocrinology Research Centre 2021-07-01
Series:Сахарный диабет
Subjects:
Online Access:https://www.dia-endojournals.ru/jour/article/view/12757
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author M. V. Shestakova
M. B. Antsiferov
A. S. Ametov
G. R. Galstyan
T. Y. Demidova
A. M. Mkrtumyan
N. A. Petunina
author_facet M. V. Shestakova
M. B. Antsiferov
A. S. Ametov
G. R. Galstyan
T. Y. Demidova
A. M. Mkrtumyan
N. A. Petunina
author_sort M. V. Shestakova
collection DOAJ
description Hyperglycemia in T2DM is based on three main mechanisms: insulin resistance, progressive β-cell dysfunction, and excess glucose production by the liver.The onset of T2DM is usually preceded by a long period of insulin resistance. Prescribing sugar drugs that affect different links of pathogenesis, reducing a steady decrease in glycemia. To date, in clinical practice, various combinations of hypoglycemic drugs are used, the choice of which is determined by the characteristics of the course of diabetes in the patient, the presence of concomitant diseases and complications of diabetes, as well as the dominant clinical problem. This resolution provides an expert council opinion on the feasibility of using a combination of alogliptin and pioglitazone in patients with type 2 diabetes.
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spelling doaj.art-e11b41f30f754ce09441600dfaac4c042024-03-20T11:48:03ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782021-07-0124219319710.14341/DM1275710879Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatmentM. V. Shestakova0M. B. Antsiferov1A. S. Ametov2G. R. Galstyan3T. Y. Demidova4A. M. Mkrtumyan5N. A. Petunina6Endocrinology Research CentreEndocrinology Dispensary of the Moscow Department of HealthRussian Medical Academy of Continuous Professional EducationEndocrinology Research CentreThe Russian National Research Medical University named after N.I. PirogovA.I. Yevdokimov Moscow State University of Medicine and DentistryI.M. Sechenov First Moscow State Medical University (Sechenov University)Hyperglycemia in T2DM is based on three main mechanisms: insulin resistance, progressive β-cell dysfunction, and excess glucose production by the liver.The onset of T2DM is usually preceded by a long period of insulin resistance. Prescribing sugar drugs that affect different links of pathogenesis, reducing a steady decrease in glycemia. To date, in clinical practice, various combinations of hypoglycemic drugs are used, the choice of which is determined by the characteristics of the course of diabetes in the patient, the presence of concomitant diseases and complications of diabetes, as well as the dominant clinical problem. This resolution provides an expert council opinion on the feasibility of using a combination of alogliptin and pioglitazone in patients with type 2 diabetes.https://www.dia-endojournals.ru/jour/article/view/12757diabetes mellitusalogliptinpioglitazonefixed combination
spellingShingle M. V. Shestakova
M. B. Antsiferov
A. S. Ametov
G. R. Galstyan
T. Y. Demidova
A. M. Mkrtumyan
N. A. Petunina
Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
Сахарный диабет
diabetes mellitus
alogliptin
pioglitazone
fixed combination
title Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
title_full Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
title_fullStr Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
title_full_unstemmed Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
title_short Possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
title_sort possibilities of application a fixed combination of alogliptin and pioglitazone for type 2 diabetes mellitus treatment
topic diabetes mellitus
alogliptin
pioglitazone
fixed combination
url https://www.dia-endojournals.ru/jour/article/view/12757
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