A review of Janus kinase/signal transducer and activator of transcription signaling and cytokines in the pain mechanism of rheumatoid arthritis

A review of Janus kinase/signal transducer and activator of transcription signaling and cytokines in the pain mechanism of rheumatoid arthritis

Rheumatoid arthritis (RA) is a progressive autoimmune disease characterized by chronic synovitis and articular destruction. Pain is the earliest and most important symptom. The Janus kinase/stat signaling pathway not only participates in the physiological processes such as the growth and differentia...

Full description

Bibliographic Details
Main Authors:	Yue Xiong, Xiaohui Song, Xiangrui Sheng, Jian Wu, Xin Chang, Tian Ren, Jin Cao, Tao Cheng, Mingjun Wang
Format:	Article
Language:	English
Published:	SAGE Publishing 2023-08-01
Series:	European Journal of Inflammation
Online Access:	https://doi.org/10.1177/1721727X231197498

Similar Items

Janus Kinase-Signal Transducer and Activator of Transcription in target therapy of cancer
by: Lior Shoev, et al.
Published: (2019-09-01)

Tofacitinib Represses the Janus Kinase-Signal Transducer and Activators of Transcription Signalling Pathway in Keratinocytes
by: Ankit Srivastava, et al.
Published: (2018-05-01)

Role of Janus kinase 1 and signal transducer and activator of transcription 3 in vitiligo
by: Samaka RM, et al.
Published: (2019-06-01)

Takinib Inhibits Inflammation in Human Rheumatoid Arthritis Synovial Fibroblasts by Targeting the Janus Kinase-Signal Transducer and Activator of Transcription 3 (JAK/STAT3) Pathway
by: Paul M. Panipinto, et al.
Published: (2021-11-01)

Azeliragon ameliorates Alzheimer's disease via the Janus tyrosine kinase and signal transducer and activator of transcription signaling pathway
by: Lijuan Yang, et al.

Baricitinib Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating the Janus Kinase/Signal Transducer and Activator of Transcription Signaling Pathway
by: Chun Dang, et al.
Published: (2021-04-01)

The oncogenic mechanisms of the Janus kinase-signal transducer and activator of transcription pathway in digestive tract tumors
by: Ruihong Zhao, et al.
Published: (2024-01-01)

Immunohistochemical study of janus kinase 1/signal transducer and activator of transcription 3 in psoriasis vulgaris
by: Farag AGA, et al.
Published: (2019-07-01)

The signal transducer and activator of transcription factors lodge in immunopathogenesis of rheumatoid arthritis
by: F. Zare, et al.
Published: (2016-05-01)

Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism
by: Yuchen Nan, et al.
Published: (2017-12-01)

Erythropoietin Attenuates Experimental Contrast-Induced Nephrology: A Role for the Janus Kinase 2/Signal Transducer and Activator of Transcription 3 Signaling Pathway
by: Jia Yang, et al.
Published: (2021-04-01)

ORF3a Protein of Severe Acute Respiratory Syndrome Coronavirus 2 Inhibits Interferon-Activated Janus Kinase/Signal Transducer and Activator of Transcription Signaling via Elevating Suppressor of Cytokine Signaling 1
by: Rong Wang, et al.
Published: (2021-09-01)

Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B.
by: Takahiro Sawada, et al.
Published: (2017-01-01)

RUSSIAN AND INTERNATIONAL EXPERIENCE IN THE APPLICATION OF THE JANUS-KINASES INHIBITOR IN RHEUMATOID ARTHRITIS
by: D. E. Karateev, et al.
Published: (2017-05-01)

Expression of Signal Transducer and Activator of Transcription 3 and Suppressor of Cytokine Signaling 3 in Urothelial Carcinoma
by: Wan-Ting Huang, et al.
Published: (2009-12-01)

Biotechnologically Produced Lavandula angustifolia Mill. Extract Rich in Rosmarinic Acid Resolves Psoriasis-Related Inflammation Through Janus Kinase/Signal Transducer and Activator of Transcription Signaling
by: Ivanka K. Koycheva, et al.
Published: (2021-04-01)

Effectiveness of Janus kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis
by: A. E. Cheberda, et al.
Published: (2024-02-01)

Clinical significance of Janus kinase inhibitors in the therapy of rheumatoid arthritis: achievements and prospects
by: V. I. Mazurov, et al.
Published: (2019-10-01)

Recombinant Human Erythropoietin Protects Myocardial Cells from Apoptosis via the Janus-Activated Kinase 2/Signal Transducer and Activator of Transcription 5 Pathway in Rats with Epilepsy
by: Bao-Xin Ma, MD, et al.
Published: (2015-12-01)

Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis
by: Jun Deng, et al.
Published: (2018-06-01)

Resveratrol suppresses neuroinflammation to alleviate mechanical allodynia by inhibiting Janus kinase 2/signal transducer and activator of transcription 3 signaling pathway in a rat model of spinal cord injury
by: Jie Han, et al.
Published: (2023-02-01)

Filgotinib, a Janus kinase 1 (JAK1)-selective inhibitor, modulates disease associated cytokines in patients with active rheumatoid arthritis
by: Taylor, P, et al.
Published: (2019)

Janus Kinase Inhibitors in Rheumatoid Arthritis: An Update on the Efficacy and Safety of Tofacitinib, Baricitinib and Upadacitinib
by: Robert Harrington, et al.
Published: (2023-10-01)

Drug Retention Rates and the Safety of Janus Kinase Inhibitors in Elderly Patients with Rheumatoid Arthritis
by: Jumpei Temmoku, et al.
Published: (2023-07-01)

Clinical Aspects of Janus Kinase (JAK) Inhibitors in the Cardiovascular System in Patients with Rheumatoid Arthritis
by: Przemysław J. Kotyla, et al.
Published: (2020-10-01)

Low-protein diets supplemented with isoleucine alleviate lipid deposition in broilers through activating 5′ adenosine monophosphate-activated protein kinase and janus kinase 2/signal transducer and activator of transcription 3 signaling pathways
by: Shengnan Ma, et al.
Published: (2023-03-01)

Corrigendum: Signal Transducer and Activator of Transcription 3 Hyperactivation Associates With Follicular Helper T Cell Differentiation and Disease Activity in Rheumatoid Arthritis
by: Jun Deng, et al.
Published: (2019-08-01)

Guggulsterone Induces Apoptosis in Multiple Myeloma Cells by Targeting High Mobility Group Box 1 via Janus Activated Kinase/Signal Transducer and Activator of Transcription Pathway
by: Sabah Akhtar, et al.
Published: (2022-11-01)

Sulfated non-anticoagulant heparin blocks Th2-induced asthma by modulating the IL-4/signal transducer and activator of transcription 6/Janus kinase 1 pathway
by: Mohamed A. Ghonim, et al.
Published: (2018-09-01)

Janus Kinase Signaling: Oncogenic Criminal of Lymphoid Cancers
by: Boheng Li, et al.
Published: (2021-10-01)

Comparison of active tuberculosis occurrence associated with Janus kinase inhibitors and biological DMARDs in rheumatoid arthritis
by: Jin-Won Kwon, et al.
Published: (2024-04-01)

Drug Retention Rates of Janus Kinase Inhibitors in Rheumatoid Arthritis Patients with Therapy-Induced Lymphopenia
by: Jumpei Temmoku, et al.
Published: (2023-07-01)

Novel Potential Janus Kinase Inhibitors with Therapeutic Prospects in Rheumatoid Arthritis Addressed by In Silico Studies
by: Andrei-Flavius Radu, et al.
Published: (2023-06-01)

Drug retention of biologics and Janus kinase inhibitors in patients with rheumatoid arthritis: the ANSWER cohort study
by: Motomu Hashimoto, et al.
Published: (2023-07-01)

A new trend in pathogenetic treatment of rheumatoid arthritis: tofacitinib, the first inhibitor of Janus kinase
by: Dmitry Evgenyevich Karateev
Published: (2014-03-01)

Mechanism of piR-1245/PIWI-like protein-2 regulating Janus kinase-2/signal transducer and activator of transcription-3/vascular endothelial growth factor signaling pathway in retinal neovascularization
by: Yong Yu, et al.
Published: (2023-01-01)

Janus kinase inhibitors in the treatment of psoriatic arthritis
by: E. Yu. Loginova, et al.
Published: (2022-02-01)

Effects of mannuronic acid (M2000) on gene expression profile of signal transducer and activator of transcription proteins (STATs) in rheumatoid arthritis patients
by: N.A.G. Gaafar, et al.
Published: (2020-07-01)

A novel treatment for psoriatic arthritis: Janus kinase inhibitors
by: Miao Chen, et al.
Published: (2020-04-01)

Increased Levels of Omega-3 Fatty Acids and DHA Are Linked to Pain Reduction in Rheumatoid Arthritis Patients Treated with Janus Kinase Inhibitors
by: Ching-Kun Chang, et al.
Published: (2021-08-01)