Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension

In 41 patients with essential hy­pertension I and II degrees telmisartan influence on parameters of intimate heodynamics and functional condition of myocardium of LV has been studied. Carried out researches have shown, that on a background of treatment with telmisartan reduction of final diastolic v...

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Main Authors: Koshlia V.I., Ben-Abid M.
Format: Article
Language:English
Published: Dnipro State Medical University 2016-09-01
Series:Medičnì Perspektivi
Subjects:
Online Access:http://medpers.dsma.dp.ua/issues/2016/N3/26-29.pdf
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author Koshlia V.I.
Ben-Abid M.
author_facet Koshlia V.I.
Ben-Abid M.
author_sort Koshlia V.I.
collection DOAJ
description In 41 patients with essential hy­pertension I and II degrees telmisartan influence on parameters of intimate heodynamics and functional condition of myocardium of LV has been studied. Carried out researches have shown, that on a background of treatment with telmisartan reduction of final diastolic volume of LV, final systolic meredional stress and final diastolic pressure of the myocardium and increase in fraction of LV ejection emission and speed of circular reduction of myocardium fibres is marked. The specified changes may be explained by improvement of plastic characteristics of the myocardium that is caused both by direct action of telmisartan on the myocardium through blockade of a local renin-angiotensin- aldosterone system, and by the mediated influence due to decrease of blood pressure and after post loading.
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spelling doaj.art-e1222c7ad0934a6593ab809dbf16365f2022-12-21T20:01:06ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042307-04042016-09-012132629Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertensionKoshlia V.I.0Ben-Abid M. 1Zaporozhye Medical Academy of Postgraduate Education Zaporozhye Medical Academy of Postgraduate Education In 41 patients with essential hy­pertension I and II degrees telmisartan influence on parameters of intimate heodynamics and functional condition of myocardium of LV has been studied. Carried out researches have shown, that on a background of treatment with telmisartan reduction of final diastolic volume of LV, final systolic meredional stress and final diastolic pressure of the myocardium and increase in fraction of LV ejection emission and speed of circular reduction of myocardium fibres is marked. The specified changes may be explained by improvement of plastic characteristics of the myocardium that is caused both by direct action of telmisartan on the myocardium through blockade of a local renin-angiotensin- aldosterone system, and by the mediated influence due to decrease of blood pressure and after post loading.http://medpers.dsma.dp.ua/issues/2016/N3/26-29.pdfessential hypertensionhemodynamicstelmisartan
spellingShingle Koshlia V.I.
Ben-Abid M.
Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
Medičnì Perspektivi
essential hypertension
hemodynamics
telmisartan
title Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
title_full Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
title_fullStr Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
title_full_unstemmed Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
title_short Features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
title_sort features of change of intracardiac gemodynamics and functional state of myocardium under the impact of telmisartan in patients with hypertension
topic essential hypertension
hemodynamics
telmisartan
url http://medpers.dsma.dp.ua/issues/2016/N3/26-29.pdf
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