Dual Specificity Phosphatase 5 Is Essential for T Cell Survival.

Dual Specificity Phosphatase 5 Is Essential for T Cell Survival.

The mitogen-activated protein kinase (MAPK) pathway regulates many key cellular processes such as differentiation, apoptosis, and survival. The final proteins in this pathway, ERK1/2, are regulated by dual specificity phosphatase 5 (DUSP5). DUSP5 is a nuclear, inducible phosphatase with high affinit...

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Bibliographic Details
Main Authors: Raman G Kutty, Gang Xin, David M Schauder, Stephanie M Cossette, Michelle Bordas, Weiguo Cui, Ramani Ramchandran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5147890?pdf=render

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