From Physics to Bioengineering: Microbial Cultivation Process Design and Feeding Rate Control Based on Relative Entropy Using Nuisance Time

From Physics to Bioengineering: Microbial Cultivation Process Design and Feeding Rate Control Based on Relative Entropy Using Nuisance Time

For historic reasons, industrial knowledge of reproducibility and restrictions imposed by regulations, open-loop feeding control approaches dominate in industrial fed-batch cultivation processes. In this study, a generic gray box biomass modeling procedure uses relative entropy as a key to approach...

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Bibliographic Details
Main Authors: Renaldas Urniezius, Vytautas Galvanauskas, Arnas Survyla, Rimvydas Simutis, Donatas Levisauskas
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Entropy
Subjects:
gray box
relative entropy
microbial cultivation
numerical convex optimization
parsimony
nuisance time
Online Access:http://www.mdpi.com/1099-4300/20/10/779

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