Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review
Abstract Background In the management of head and neck cancer (HNC) patients, local recurrence is a common cause of treatment failure. Only a few patients with recurrent HNC (rHNC) are eligible for salvage surgery and the majority of patients receive systemic therapy and radiotherapy. In recent year...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-022-03774-0 |
| _version_ | 1828170309432246272 |
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| author | Yue Li Yuliang Jiang Bin Qiu Haitao Sun Junjie Wang |
| author_facet | Yue Li Yuliang Jiang Bin Qiu Haitao Sun Junjie Wang |
| author_sort | Yue Li |
| collection | DOAJ |
| description | Abstract Background In the management of head and neck cancer (HNC) patients, local recurrence is a common cause of treatment failure. Only a few patients with recurrent HNC (rHNC) are eligible for salvage surgery and the majority of patients receive systemic therapy and radiotherapy. In recent years, with the development of irradiation technology, radiotherapy for rHNC patients has markedly attracted clinicians’ attention and its therapeutic effects on patients with end-stage cancer are worthy of investigation as well. Methods Several studies have investigated the role of radiotherapy in the treatment of rHNC patients. We reviewed retrospective reports and prospective trials published in recent decades that concentrated on the management of rHNC. Results A growing body of evidence supported the application of irradiation to rHNC patients. According to the results of this review, current radiotherapy could achieve a better efficacy with a lower incidence of toxicity. Conclusion Radiotherapy is a promising treatment for rHNC patients. |
| first_indexed | 2024-04-12T03:07:44Z |
| format | Article |
| id | doaj.art-e12b2d4ed10e4fc7bf10bf8f5fbf1548 |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-04-12T03:07:44Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-e12b2d4ed10e4fc7bf10bf8f5fbf15482022-12-22T03:50:28ZengBMCJournal of Translational Medicine1479-58762022-12-0120112710.1186/s12967-022-03774-0Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art reviewYue Li0Yuliang Jiang1Bin Qiu2Haitao Sun3Junjie Wang4Department of Radiation Oncology, Peking University Third HospitalDepartment of Radiation Oncology, Peking University Third HospitalDepartment of Radiation Oncology, Peking University Third HospitalDepartment of Radiation Oncology, Peking University Third HospitalDepartment of Radiation Oncology, Peking University Third HospitalAbstract Background In the management of head and neck cancer (HNC) patients, local recurrence is a common cause of treatment failure. Only a few patients with recurrent HNC (rHNC) are eligible for salvage surgery and the majority of patients receive systemic therapy and radiotherapy. In recent years, with the development of irradiation technology, radiotherapy for rHNC patients has markedly attracted clinicians’ attention and its therapeutic effects on patients with end-stage cancer are worthy of investigation as well. Methods Several studies have investigated the role of radiotherapy in the treatment of rHNC patients. We reviewed retrospective reports and prospective trials published in recent decades that concentrated on the management of rHNC. Results A growing body of evidence supported the application of irradiation to rHNC patients. According to the results of this review, current radiotherapy could achieve a better efficacy with a lower incidence of toxicity. Conclusion Radiotherapy is a promising treatment for rHNC patients.https://doi.org/10.1186/s12967-022-03774-0Head and neck cancerRecurrenceExternal beam radiotherapyBrachytherapy |
| spellingShingle | Yue Li Yuliang Jiang Bin Qiu Haitao Sun Junjie Wang Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review Journal of Translational Medicine Head and neck cancer Recurrence External beam radiotherapy Brachytherapy |
| title | Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review |
| title_full | Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review |
| title_fullStr | Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review |
| title_full_unstemmed | Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review |
| title_short | Current radiotherapy for recurrent head and neck cancer in the modern era: a state-of-the-art review |
| title_sort | current radiotherapy for recurrent head and neck cancer in the modern era a state of the art review |
| topic | Head and neck cancer Recurrence External beam radiotherapy Brachytherapy |
| url | https://doi.org/10.1186/s12967-022-03774-0 |
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