C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques

C-Reactive Protein Binds to Cholesterol Crystals and Co-Localizes with the Terminal Complement Complex in Human Atherosclerotic Plaques

Inflammation is a part of the initial process leading to atherosclerosis and cholesterol crystals (CC), found in atherosclerotic plaques, which are known to induce complement activation. The pentraxins C-reactive protein (CRP), long pentraxin 3 (PTX3), and serum amyloid P component (SAP) are serum p...

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Detalhes bibliográficos
Principais autores: Katrine Pilely, Stefano Fumagalli, Anne Rosbjerg, Ninette Genster, Mikkel-Ole Skjoedt, Carlo Perego, Angela M. R. Ferrante, Maria-Grazia De Simoni, Peter Garred
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2017-08-01
coleção:Frontiers in Immunology
Assuntos:
atherosclerosis
complement activation
cholesterol crystals
C-reactive protein
pentraxin 3
serum amyloid P component
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01040/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01040/full

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