Clinical and imaging features of reversible splenial lesion syndrome with language disorder
Reversible splenial lesion syndrome (RESLES) is a single-stage non-specific syndrome with unclear pathogenesis. There has been no report on answer delay in patients with RESLES. We report a female patient who was admitted to our department for mixed aphasia accompanied by cognitive impairment. Durin...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2020-06-01
|
| Series: | Translational Neuroscience |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tnsci-2020-0126 |
| _version_ | 1828180531325435904 |
|---|---|
| author | Tang Yi Zhang Dong Ge Jian Jin Jing Liu Yumeng Chen Siyuan He Mingli |
| author_facet | Tang Yi Zhang Dong Ge Jian Jin Jing Liu Yumeng Chen Siyuan He Mingli |
| author_sort | Tang Yi |
| collection | DOAJ |
| description | Reversible splenial lesion syndrome (RESLES) is a single-stage non-specific syndrome with unclear pathogenesis. There has been no report on answer delay in patients with RESLES. We report a female patient who was admitted to our department for mixed aphasia accompanied by cognitive impairment. During the rapid improvement of aphasia, there was a clear phase of language output response delay accompanied by resolution of imaging lesions. We analyzed the course and the examination results of the patient and speculated the cause and pathogenesis. RESLES-relevant knowledge was systematically reviewed, which will help doctors in the classification of cerebral function and the diagnosis of RESLES. The specific language and cognitive impairment may be associated with the damage of contact fibers in the bilateral primary and secondary sensory and motor cortices. |
| first_indexed | 2024-04-12T05:45:46Z |
| format | Article |
| id | doaj.art-e131ba90d3c64994becdccb15dbe2404 |
| institution | Directory Open Access Journal |
| issn | 2081-6936 |
| language | English |
| last_indexed | 2024-04-12T05:45:46Z |
| publishDate | 2020-06-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Translational Neuroscience |
| spelling | doaj.art-e131ba90d3c64994becdccb15dbe24042022-12-22T03:45:28ZengDe GruyterTranslational Neuroscience2081-69362020-06-0111121021410.1515/tnsci-2020-0126tnsci-2020-0126Clinical and imaging features of reversible splenial lesion syndrome with language disorderTang Yi0Zhang Dong1Ge Jian2Jin Jing3Liu Yumeng4Chen Siyuan5He Mingli6Department of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaDepartment of Neurology, The affiliated Lianyungang Hospital of Xuzhou Medical University, Tongguan North Road, No. 182, Haizhou District, Lianyungang, Jiangsu, ChinaReversible splenial lesion syndrome (RESLES) is a single-stage non-specific syndrome with unclear pathogenesis. There has been no report on answer delay in patients with RESLES. We report a female patient who was admitted to our department for mixed aphasia accompanied by cognitive impairment. During the rapid improvement of aphasia, there was a clear phase of language output response delay accompanied by resolution of imaging lesions. We analyzed the course and the examination results of the patient and speculated the cause and pathogenesis. RESLES-relevant knowledge was systematically reviewed, which will help doctors in the classification of cerebral function and the diagnosis of RESLES. The specific language and cognitive impairment may be associated with the damage of contact fibers in the bilateral primary and secondary sensory and motor cortices.https://doi.org/10.1515/tnsci-2020-0126reversible splenial lesion syndromecorpus callosumsplenium of the corpus callosumcognitive impairmentlanguage impairment |
| spellingShingle | Tang Yi Zhang Dong Ge Jian Jin Jing Liu Yumeng Chen Siyuan He Mingli Clinical and imaging features of reversible splenial lesion syndrome with language disorder Translational Neuroscience reversible splenial lesion syndrome corpus callosum splenium of the corpus callosum cognitive impairment language impairment |
| title | Clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| title_full | Clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| title_fullStr | Clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| title_full_unstemmed | Clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| title_short | Clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| title_sort | clinical and imaging features of reversible splenial lesion syndrome with language disorder |
| topic | reversible splenial lesion syndrome corpus callosum splenium of the corpus callosum cognitive impairment language impairment |
| url | https://doi.org/10.1515/tnsci-2020-0126 |
| work_keys_str_mv | AT tangyi clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT zhangdong clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT gejian clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT jinjing clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT liuyumeng clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT chensiyuan clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder AT hemingli clinicalandimagingfeaturesofreversiblespleniallesionsyndromewithlanguagedisorder |