A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis

Phenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with...

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Main Authors: Ancuta Dinu, Constantin Apetrei
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/20/9/2496
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author Ancuta Dinu
Constantin Apetrei
author_facet Ancuta Dinu
Constantin Apetrei
author_sort Ancuta Dinu
collection DOAJ
description Phenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with a genetic disorder called phenylketonuria. The accumulation of phenylalanine and of some metabolites in the body is dangerous and may cause convulsions, brain damage and mental retardation. Determining the concentration of phenylalanine in different biologic fluids is very important because it can provide information about the health status of the individuals envisaged. Since such determinations may be made by using electrochemical sensors and biosensors, numerous researchers have developed such sensors for phenylalanine detection and different sensitive materials were used in order to improve the selectivity, sensitivity and detection limit. The present review aims at presenting the design and performance of some electrochemical bio (sensors) traditionally used for phenylalanine detection as reported in a series of relevant scientific papers published in the last decade.
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spelling doaj.art-e1377d0ec48f40bab4961ced0932a07c2023-11-19T22:57:12ZengMDPI AGSensors1424-82202020-04-01209249610.3390/s20092496A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine ElectroanalysisAncuta Dinu0Constantin Apetrei1Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaPhenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with a genetic disorder called phenylketonuria. The accumulation of phenylalanine and of some metabolites in the body is dangerous and may cause convulsions, brain damage and mental retardation. Determining the concentration of phenylalanine in different biologic fluids is very important because it can provide information about the health status of the individuals envisaged. Since such determinations may be made by using electrochemical sensors and biosensors, numerous researchers have developed such sensors for phenylalanine detection and different sensitive materials were used in order to improve the selectivity, sensitivity and detection limit. The present review aims at presenting the design and performance of some electrochemical bio (sensors) traditionally used for phenylalanine detection as reported in a series of relevant scientific papers published in the last decade.https://www.mdpi.com/1424-8220/20/9/2496phenylalaninesensorbiosensorelectrochemistryphenylketonuria
spellingShingle Ancuta Dinu
Constantin Apetrei
A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
Sensors
phenylalanine
sensor
biosensor
electrochemistry
phenylketonuria
title A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
title_full A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
title_fullStr A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
title_full_unstemmed A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
title_short A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
title_sort review on electrochemical sensors and biosensors used in phenylalanine electroanalysis
topic phenylalanine
sensor
biosensor
electrochemistry
phenylketonuria
url https://www.mdpi.com/1424-8220/20/9/2496
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