A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis
Phenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with...
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MDPI AG
2020-04-01
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Online Access: | https://www.mdpi.com/1424-8220/20/9/2496 |
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author | Ancuta Dinu Constantin Apetrei |
author_facet | Ancuta Dinu Constantin Apetrei |
author_sort | Ancuta Dinu |
collection | DOAJ |
description | Phenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with a genetic disorder called phenylketonuria. The accumulation of phenylalanine and of some metabolites in the body is dangerous and may cause convulsions, brain damage and mental retardation. Determining the concentration of phenylalanine in different biologic fluids is very important because it can provide information about the health status of the individuals envisaged. Since such determinations may be made by using electrochemical sensors and biosensors, numerous researchers have developed such sensors for phenylalanine detection and different sensitive materials were used in order to improve the selectivity, sensitivity and detection limit. The present review aims at presenting the design and performance of some electrochemical bio (sensors) traditionally used for phenylalanine detection as reported in a series of relevant scientific papers published in the last decade. |
first_indexed | 2024-03-10T20:10:55Z |
format | Article |
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institution | Directory Open Access Journal |
issn | 1424-8220 |
language | English |
last_indexed | 2024-03-10T20:10:55Z |
publishDate | 2020-04-01 |
publisher | MDPI AG |
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series | Sensors |
spelling | doaj.art-e1377d0ec48f40bab4961ced0932a07c2023-11-19T22:57:12ZengMDPI AGSensors1424-82202020-04-01209249610.3390/s20092496A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine ElectroanalysisAncuta Dinu0Constantin Apetrei1Department of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaDepartment of Chemistry, Physics and Environment, Faculty of Sciences and Environment, “Dunărea de Jos” University of Galaţi, 47 Domneasca Street, 800008 Galaţi, RomaniaPhenylalanine is an amino acid found in breast milk and in many foods, being an essential nutrient. This amino acid is very important for the human body because it is transformed into tyrosine and, subsequently, into catecholamine neurotransmitters. However, there are individuals who were born with a genetic disorder called phenylketonuria. The accumulation of phenylalanine and of some metabolites in the body is dangerous and may cause convulsions, brain damage and mental retardation. Determining the concentration of phenylalanine in different biologic fluids is very important because it can provide information about the health status of the individuals envisaged. Since such determinations may be made by using electrochemical sensors and biosensors, numerous researchers have developed such sensors for phenylalanine detection and different sensitive materials were used in order to improve the selectivity, sensitivity and detection limit. The present review aims at presenting the design and performance of some electrochemical bio (sensors) traditionally used for phenylalanine detection as reported in a series of relevant scientific papers published in the last decade.https://www.mdpi.com/1424-8220/20/9/2496phenylalaninesensorbiosensorelectrochemistryphenylketonuria |
spellingShingle | Ancuta Dinu Constantin Apetrei A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis Sensors phenylalanine sensor biosensor electrochemistry phenylketonuria |
title | A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis |
title_full | A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis |
title_fullStr | A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis |
title_full_unstemmed | A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis |
title_short | A Review on Electrochemical Sensors and Biosensors Used in Phenylalanine Electroanalysis |
title_sort | review on electrochemical sensors and biosensors used in phenylalanine electroanalysis |
topic | phenylalanine sensor biosensor electrochemistry phenylketonuria |
url | https://www.mdpi.com/1424-8220/20/9/2496 |
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