Erectile dysfunction as a possible important side effect of metformin: A case report
Metformin-induced sexual dysfunction is rare in patients with diabetes mellitus. Herein, we present the case of a 57-year-old man newly diagnosed with type 2 diabetes mellitus who developed erectile dysfunction following treatment with metformin 500 mg BD. Prior to taking metformin, he had well-cont...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Academy of Family Physicians of Malaysia
2023-04-01
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| Series: | Malaysian Family Physician |
| Subjects: | |
| Online Access: | https://e-mfp.org/wp-content/uploads/18.20R1CRErectiledysfunctionapossibleimportant1.pdf |
| _version_ | 1797835980407832576 |
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| author | Min Huang Ngu Rosnani Zakaria Maryam Mohd Zulkifli Rahiza Bt Ab Rahman |
| author_facet | Min Huang Ngu Rosnani Zakaria Maryam Mohd Zulkifli Rahiza Bt Ab Rahman |
| author_sort | Min Huang Ngu |
| collection | DOAJ |
| description | Metformin-induced sexual dysfunction is rare in patients with diabetes mellitus. Herein, we present the case of a 57-year-old man newly diagnosed with type 2 diabetes mellitus who developed erectile dysfunction following treatment with metformin 500 mg BD. Prior to taking metformin, he had well-controlled hypertension, hyperlipidaemia and normal sexual function. Two weeks after beginning metformin therapy, he was diagnosed with erectile dysfunction after experiencing persistent difficulty achieving an erection. After discontinuation of metformin, his sexual function returned to normal. To determine whether sexual dysfunction is caused by metformin, we rechallenged the patient with metformin 500 mg BD. After 15 days, he became impotent again, confirming that metformin was the most likely cause of his sexual problem. Metformin was stopped, and his sexual function returned to normal after 3 weeks. The adverse reaction is ‘probable’ according to the World Health Organization–Uppsala Monitoring Centre. |
| first_indexed | 2024-04-09T15:02:21Z |
| format | Article |
| id | doaj.art-e1382babfb2847498b52231a1af304d7 |
| institution | Directory Open Access Journal |
| issn | 1985-207X 1985-2274 |
| language | English |
| last_indexed | 2024-04-09T15:02:21Z |
| publishDate | 2023-04-01 |
| publisher | Academy of Family Physicians of Malaysia |
| record_format | Article |
| series | Malaysian Family Physician |
| spelling | doaj.art-e1382babfb2847498b52231a1af304d72023-05-01T16:48:27ZengAcademy of Family Physicians of MalaysiaMalaysian Family Physician1985-207X1985-22742023-04-01182010.51866/cr.207Erectile dysfunction as a possible important side effect of metformin: A case reportMin Huang NguRosnani ZakariaMaryam Mohd ZulkifliRahiza Bt Ab RahmanMetformin-induced sexual dysfunction is rare in patients with diabetes mellitus. Herein, we present the case of a 57-year-old man newly diagnosed with type 2 diabetes mellitus who developed erectile dysfunction following treatment with metformin 500 mg BD. Prior to taking metformin, he had well-controlled hypertension, hyperlipidaemia and normal sexual function. Two weeks after beginning metformin therapy, he was diagnosed with erectile dysfunction after experiencing persistent difficulty achieving an erection. After discontinuation of metformin, his sexual function returned to normal. To determine whether sexual dysfunction is caused by metformin, we rechallenged the patient with metformin 500 mg BD. After 15 days, he became impotent again, confirming that metformin was the most likely cause of his sexual problem. Metformin was stopped, and his sexual function returned to normal after 3 weeks. The adverse reaction is ‘probable’ according to the World Health Organization–Uppsala Monitoring Centre.https://e-mfp.org/wp-content/uploads/18.20R1CRErectiledysfunctionapossibleimportant1.pdfmetforminerectile dysfunctiondiabetes mellitussexual dysfunction |
| spellingShingle | Min Huang Ngu Rosnani Zakaria Maryam Mohd Zulkifli Rahiza Bt Ab Rahman Erectile dysfunction as a possible important side effect of metformin: A case report Malaysian Family Physician metformin erectile dysfunction diabetes mellitus sexual dysfunction |
| title | Erectile dysfunction as a possible important side effect of metformin: A case report |
| title_full | Erectile dysfunction as a possible important side effect of metformin: A case report |
| title_fullStr | Erectile dysfunction as a possible important side effect of metformin: A case report |
| title_full_unstemmed | Erectile dysfunction as a possible important side effect of metformin: A case report |
| title_short | Erectile dysfunction as a possible important side effect of metformin: A case report |
| title_sort | erectile dysfunction as a possible important side effect of metformin a case report |
| topic | metformin erectile dysfunction diabetes mellitus sexual dysfunction |
| url | https://e-mfp.org/wp-content/uploads/18.20R1CRErectiledysfunctionapossibleimportant1.pdf |
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