Design and Study of Nanoceria Modified by 5-Fluorouracil for Gel and Polymer Dermal Film Preparation

Design and Study of Nanoceria Modified by 5-Fluorouracil for Gel and Polymer Dermal Film Preparation

In this work we studied nanoceria (CeO<sub>2</sub>NPs) and nanoceria modified by 5-fluorouracil (5FU) as potential APIs. Nanoceria were synthesized by precipitation in a matrix of hydroxyethyl cellulose or hydroxypropylmethyl cellulose, using cerium (III) nitrate and meglumine. Nanoceria...

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Bibliographic Details
Main Authors: Nina Melnikova, Ilya Sheferov, Dmitry Panteleev, Anastasia Emasheva, Irina Druzhkova, Nadezhda Ignatova, Tatiana Mishchenko, Maria Vedunova
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Pharmaceuticals
Subjects:
nanoceria modified by 5FU
polymer dermal films
hydrogel
cytotoxicity
Online Access:https://www.mdpi.com/1424-8247/16/8/1082

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