Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019

Background The North Africa and Middle East (NAME) region has one of the highest burdens of ischemic heart disease (IHD) worldwide. This study reports the contemporary epidemiology of IHD in NAME. Methods and Results We estimated the incidence, prevalence, deaths, years of life lost, years lived wit...

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Main Authors: Arya Aminorroaya, Sahar Saeedi Moghaddam, Hamed Tavolinejad, Zahra Aryan, Behnam Heidari, Hedyeh Ebrahimi, Mohammadreza Naderian, Parnian Shobeiri, Ali Ghanbari, Nazila Rezaei, Mohammad‐Reza Malekpour, Rosa Haghshenas, Negar Rezaei, Bagher Larijani, Farshad Farzadfar
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.123.030165
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author Arya Aminorroaya
Sahar Saeedi Moghaddam
Hamed Tavolinejad
Zahra Aryan
Behnam Heidari
Hedyeh Ebrahimi
Mohammadreza Naderian
Parnian Shobeiri
Ali Ghanbari
Nazila Rezaei
Mohammad‐Reza Malekpour
Rosa Haghshenas
Negar Rezaei
Bagher Larijani
Farshad Farzadfar
author_facet Arya Aminorroaya
Sahar Saeedi Moghaddam
Hamed Tavolinejad
Zahra Aryan
Behnam Heidari
Hedyeh Ebrahimi
Mohammadreza Naderian
Parnian Shobeiri
Ali Ghanbari
Nazila Rezaei
Mohammad‐Reza Malekpour
Rosa Haghshenas
Negar Rezaei
Bagher Larijani
Farshad Farzadfar
author_sort Arya Aminorroaya
collection DOAJ
description Background The North Africa and Middle East (NAME) region has one of the highest burdens of ischemic heart disease (IHD) worldwide. This study reports the contemporary epidemiology of IHD in NAME. Methods and Results We estimated the incidence, prevalence, deaths, years of life lost, years lived with disability, disability‐adjusted life years (DALYs), and premature mortality of IHD, and its attributable risk factors in NAME from 1990 to 2019 using the results of the GBD (Global Burden of Disease study 2019). In 2019, 0.8 million lives and 18.0 million DALYs were lost due to IHD in NAME. From 1990 to 2019, the age‐standardized DALY rate of IHD significantly decreased by 33.3%, mostly due to the reduction of years of life lost rather than years lived with disability. In 2019, the proportion of premature death attributable to IHD was higher in NAME compared with global measures: 26.8% versus 16.9% for women and 18.4% versus 14.8% for men, respectively. The age‐standardized DALY rate of IHD attributed to metabolic risks, behavioral risks, and environmental/occupational risks significantly decreased by 28.7%, 37.8%, and 36.4%, respectively. Dietary risk factors, high systolic blood pressure, and high low‐density lipoprotein cholesterol were the top 3 risks contributing to the IHD burden in most countries of NAME in 2019. Conclusions In 2019, IHD was the leading cause of death and lost DALYs in NAME, where premature death due to IHD was greater than the global average. Despite the great reduction in the age‐standardized DALYs of IHD in NAME from 1990 to 2019, this region still had the second‐highest burden of IHD in 2019 globally.
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spelling doaj.art-e13dd01fe84b4b99a72c29b7a2e6c0be2024-02-24T04:04:20ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-01-0113210.1161/JAHA.123.030165Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019Arya Aminorroaya0Sahar Saeedi Moghaddam1Hamed Tavolinejad2Zahra Aryan3Behnam Heidari4Hedyeh Ebrahimi5Mohammadreza Naderian6Parnian Shobeiri7Ali Ghanbari8Nazila Rezaei9Mohammad‐Reza Malekpour10Rosa Haghshenas11Negar Rezaei12Bagher Larijani13Farshad Farzadfar14Section of Cardiovascular Medicine, Department of Internal Medicine Yale School of Medicine New Haven CT USANon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranDepartment of Medicine Rutgers New Jersey Medical School Newark NJ USAEndocrinology and Metabolism Research Center (EMRC), Vali‐Asr Hospital, School of Medicine Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranBackground The North Africa and Middle East (NAME) region has one of the highest burdens of ischemic heart disease (IHD) worldwide. This study reports the contemporary epidemiology of IHD in NAME. Methods and Results We estimated the incidence, prevalence, deaths, years of life lost, years lived with disability, disability‐adjusted life years (DALYs), and premature mortality of IHD, and its attributable risk factors in NAME from 1990 to 2019 using the results of the GBD (Global Burden of Disease study 2019). In 2019, 0.8 million lives and 18.0 million DALYs were lost due to IHD in NAME. From 1990 to 2019, the age‐standardized DALY rate of IHD significantly decreased by 33.3%, mostly due to the reduction of years of life lost rather than years lived with disability. In 2019, the proportion of premature death attributable to IHD was higher in NAME compared with global measures: 26.8% versus 16.9% for women and 18.4% versus 14.8% for men, respectively. The age‐standardized DALY rate of IHD attributed to metabolic risks, behavioral risks, and environmental/occupational risks significantly decreased by 28.7%, 37.8%, and 36.4%, respectively. Dietary risk factors, high systolic blood pressure, and high low‐density lipoprotein cholesterol were the top 3 risks contributing to the IHD burden in most countries of NAME in 2019. Conclusions In 2019, IHD was the leading cause of death and lost DALYs in NAME, where premature death due to IHD was greater than the global average. Despite the great reduction in the age‐standardized DALYs of IHD in NAME from 1990 to 2019, this region still had the second‐highest burden of IHD in 2019 globally.https://www.ahajournals.org/doi/10.1161/JAHA.123.030165coronary artery diseaseepidemiologyglobal burden of diseaseischemic heart diseasemortalityNorth Africa and Middle East
spellingShingle Arya Aminorroaya
Sahar Saeedi Moghaddam
Hamed Tavolinejad
Zahra Aryan
Behnam Heidari
Hedyeh Ebrahimi
Mohammadreza Naderian
Parnian Shobeiri
Ali Ghanbari
Nazila Rezaei
Mohammad‐Reza Malekpour
Rosa Haghshenas
Negar Rezaei
Bagher Larijani
Farshad Farzadfar
Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
coronary artery disease
epidemiology
global burden of disease
ischemic heart disease
mortality
North Africa and Middle East
title Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
title_full Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
title_fullStr Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
title_full_unstemmed Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
title_short Burden of Ischemic Heart Disease and Its Attributable Risk Factors in North Africa and the Middle East, 1990 to 2019: Results From the GBD Study 2019
title_sort burden of ischemic heart disease and its attributable risk factors in north africa and the middle east 1990 to 2019 results from the gbd study 2019
topic coronary artery disease
epidemiology
global burden of disease
ischemic heart disease
mortality
North Africa and Middle East
url https://www.ahajournals.org/doi/10.1161/JAHA.123.030165
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