Potential Therapeutic Target Protein Tyrosine Phosphatase-1B for Modulation of Insulin Resistance with Polyphenols and Its Quantitative Structure–Activity Relationship

Potential Therapeutic Target Protein Tyrosine Phosphatase-1B for Modulation of Insulin Resistance with Polyphenols and Its Quantitative Structure–Activity Relationship

The increase in the number of cases of type 2 diabetes mellitus (T2DM) and the complications associated with the side effects of chemical/synthetic drugs have raised concerns about the safety of the drugs. Hence, there is an urgent need to explore and identify natural bioactive compounds as alternat...

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Bibliographic Details
Main Authors: Prangya Rath, Anuj Ranjan, Arabinda Ghosh, Abhishek Chauhan, Manisha Gurnani, Hardeep Singh Tuli, Hamza Habeeballah, Mustfa F. Alkhanani, Shafiul Haque, Kuldeep Dhama, Naval Kumar Verma, Tanu Jindal
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
catalytic active site
diabetes
docking
insulin resistance
molecular dynamic simulation
polyphenols
Online Access:https://www.mdpi.com/1420-3049/27/7/2212

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