Safety assessment of essential medicines for elderly people: a bibliographic survey

Certain medicines are considered potentially inappropriate (PIM) for elderly people as they increase the risk of adverse drug events (ADE) and because safer alternative therapies are available on the market. In this context, in order to identify the instruments that assess the quality of medical pre...

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Main Authors: Fabiana Rossi Varallo, Fernanda Mariana de Oliveira, Patrícia de Carvalho Mastroianni
Format: Article
Language:English
Published: Universidade de São Paulo 2014-04-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200269&lng=en&tlng=en
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author Fabiana Rossi Varallo
Fernanda Mariana de Oliveira
Patrícia de Carvalho Mastroianni
author_facet Fabiana Rossi Varallo
Fernanda Mariana de Oliveira
Patrícia de Carvalho Mastroianni
author_sort Fabiana Rossi Varallo
collection DOAJ
description Certain medicines are considered potentially inappropriate (PIM) for elderly people as they increase the risk of adverse drug events (ADE) and because safer alternative therapies are available on the market. In this context, in order to identify the instruments that assess the quality of medical prescriptions for elderly and to determine which drugs are considered PIM, a bibliographic survey was conducted in PUBMED, LILACS and PAHO databases, in February and March/2010. The search strategy included the use of health descriptors and a manual search in the references cited by selected papers. During the period of data collection, 15 instruments were identified. In 2012, with the publication of the update of Beers criteria, this instrument was included in the study. We identified 163 PIM of 25 therapeutic classes, of which 125 (76.7%) are marketed in Brazil. Of these, 31 (24.8%) are essential medicines (RENAME 2012), of which 13 have safer therapeutic equivalents and 19 (15.2%) are over-the-counter drugs. Data suggest the need for inclusion of safer alternatives for the elderly in the national list of essential medicines and the pharmaceutical care for early detection of ADE in this age group, in order to contribute to the safe use of medicines.
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spelling doaj.art-e145893f13854c9fb82713656dd57a112022-12-21T19:05:25ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902014-04-0150226928410.1590/S1984-82502014000200006S1984-82502014000200269Safety assessment of essential medicines for elderly people: a bibliographic surveyFabiana Rossi VaralloFernanda Mariana de OliveiraPatrícia de Carvalho MastroianniCertain medicines are considered potentially inappropriate (PIM) for elderly people as they increase the risk of adverse drug events (ADE) and because safer alternative therapies are available on the market. In this context, in order to identify the instruments that assess the quality of medical prescriptions for elderly and to determine which drugs are considered PIM, a bibliographic survey was conducted in PUBMED, LILACS and PAHO databases, in February and March/2010. The search strategy included the use of health descriptors and a manual search in the references cited by selected papers. During the period of data collection, 15 instruments were identified. In 2012, with the publication of the update of Beers criteria, this instrument was included in the study. We identified 163 PIM of 25 therapeutic classes, of which 125 (76.7%) are marketed in Brazil. Of these, 31 (24.8%) are essential medicines (RENAME 2012), of which 13 have safer therapeutic equivalents and 19 (15.2%) are over-the-counter drugs. Data suggest the need for inclusion of safer alternatives for the elderly in the national list of essential medicines and the pharmaceutical care for early detection of ADE in this age group, in order to contribute to the safe use of medicines.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200269&lng=en&tlng=enIdoso/prescrição de medicamentosMedicação/errosMedicamentos/prescrição inadequadaMedicamentos/efeitos adversos/controleMedicamentos/uso seguroMedicação de risco/controleMonitoramento farmacoterapêutico
spellingShingle Fabiana Rossi Varallo
Fernanda Mariana de Oliveira
Patrícia de Carvalho Mastroianni
Safety assessment of essential medicines for elderly people: a bibliographic survey
Brazilian Journal of Pharmaceutical Sciences
Idoso/prescrição de medicamentos
Medicação/erros
Medicamentos/prescrição inadequada
Medicamentos/efeitos adversos/controle
Medicamentos/uso seguro
Medicação de risco/controle
Monitoramento farmacoterapêutico
title Safety assessment of essential medicines for elderly people: a bibliographic survey
title_full Safety assessment of essential medicines for elderly people: a bibliographic survey
title_fullStr Safety assessment of essential medicines for elderly people: a bibliographic survey
title_full_unstemmed Safety assessment of essential medicines for elderly people: a bibliographic survey
title_short Safety assessment of essential medicines for elderly people: a bibliographic survey
title_sort safety assessment of essential medicines for elderly people a bibliographic survey
topic Idoso/prescrição de medicamentos
Medicação/erros
Medicamentos/prescrição inadequada
Medicamentos/efeitos adversos/controle
Medicamentos/uso seguro
Medicação de risco/controle
Monitoramento farmacoterapêutico
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000200269&lng=en&tlng=en
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AT patriciadecarvalhomastroianni safetyassessmentofessentialmedicinesforelderlypeopleabibliographicsurvey