A Case of Wilson’s Disease Mimicking Malignancy
Wilson’s disease is a rare autosomal recessive inherited disorder of copper metabolism that causes various degrees of hepatic and neuropsychiatric symptoms. The condition is due to mutations in the ATP7B gene localized to arm 13q. The clinical signs are complex. The accumulation of copper in the bra...
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2014-03-01
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| Series: | Haseki Tıp Bülteni |
| Subjects: | |
| Online Access: | http://www.hasekidergisi.com/article_4735/A-Case-Of-Wilsons-Disease-Mimicking-Malignancy |
| _version_ | 1797923505527848960 |
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| author | Ahmet Akın Şakir Özgür Keşkek Mehmet Aliustaoğlu Nedime Şahinoğlu-Keşkek |
| author_facet | Ahmet Akın Şakir Özgür Keşkek Mehmet Aliustaoğlu Nedime Şahinoğlu-Keşkek |
| author_sort | Ahmet Akın |
| collection | DOAJ |
| description | Wilson’s disease is a rare autosomal recessive inherited disorder of copper metabolism that causes various degrees of hepatic and neuropsychiatric symptoms. The condition is due to mutations in the ATP7B gene localized to arm 13q. The clinical signs are complex. The accumulation of copper in the brain causes tremor, dysartria and psychiatric problems. The deposits in the liver can lead to acute, chronic and progressive hepatitis and cirrhosis. Wilson’s disease is the first liver disease for which an effective pharmacological treatment was found. In this paper, we gave particular importance to liver involvement in Wilson’s disease and emphasized that the disease can be confused with metastatic liver diseases. (The Medical Bulletin of Haseki 2014; 52: 64-6) |
| first_indexed | 2024-04-10T14:47:21Z |
| format | Article |
| id | doaj.art-e1461a15f70743f281d813dec28e1de9 |
| institution | Directory Open Access Journal |
| issn | 1302-0072 2147-2688 |
| language | English |
| last_indexed | 2024-04-10T14:47:21Z |
| publishDate | 2014-03-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Haseki Tıp Bülteni |
| spelling | doaj.art-e1461a15f70743f281d813dec28e1de92023-02-15T16:07:46ZengGalenos YayineviHaseki Tıp Bülteni1302-00722147-26882014-03-01521646610.4274/Haseki.1297A Case of Wilson’s Disease Mimicking MalignancyAhmet Akın0Şakir Özgür Keşkek1Mehmet Aliustaoğlu2Nedime Şahinoğlu-Keşkek3Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, İstanbul, TürkiyeNumune Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, Adana, TürkiyeDr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Dahiliye Kliniği, İstanbul, TürkiyeNumune Eğitim ve Araştırma Hastanesi, Göz Hastalıkları Kliniği, Adana, TürkiyeWilson’s disease is a rare autosomal recessive inherited disorder of copper metabolism that causes various degrees of hepatic and neuropsychiatric symptoms. The condition is due to mutations in the ATP7B gene localized to arm 13q. The clinical signs are complex. The accumulation of copper in the brain causes tremor, dysartria and psychiatric problems. The deposits in the liver can lead to acute, chronic and progressive hepatitis and cirrhosis. Wilson’s disease is the first liver disease for which an effective pharmacological treatment was found. In this paper, we gave particular importance to liver involvement in Wilson’s disease and emphasized that the disease can be confused with metastatic liver diseases. (The Medical Bulletin of Haseki 2014; 52: 64-6)http://www.hasekidergisi.com/article_4735/A-Case-Of-Wilsons-Disease-Mimicking-MalignancyWilson’s diseasemalignancyliver |
| spellingShingle | Ahmet Akın Şakir Özgür Keşkek Mehmet Aliustaoğlu Nedime Şahinoğlu-Keşkek A Case of Wilson’s Disease Mimicking Malignancy Haseki Tıp Bülteni Wilson’s disease malignancy liver |
| title | A Case of Wilson’s Disease Mimicking Malignancy |
| title_full | A Case of Wilson’s Disease Mimicking Malignancy |
| title_fullStr | A Case of Wilson’s Disease Mimicking Malignancy |
| title_full_unstemmed | A Case of Wilson’s Disease Mimicking Malignancy |
| title_short | A Case of Wilson’s Disease Mimicking Malignancy |
| title_sort | case of wilson s disease mimicking malignancy |
| topic | Wilson’s disease malignancy liver |
| url | http://www.hasekidergisi.com/article_4735/A-Case-Of-Wilsons-Disease-Mimicking-Malignancy |
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