Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region
Abstract INTRODUCTION: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region. METHODS: The isolates were identified by MALDI-TOF and the carbapenemase-...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2020-11-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100602&tlng=en |
| _version_ | 1811244662459990016 |
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| author | Edlainny Araujo Ribeiro Ana Cristina Gales Ana Paula Streling de Oliveira Danilo Dias Coelho Rodrigo Alves de Oliveira Irmtraut Araci Hoffmann Pfrimer José Rodrigues do Carmo Filho |
| author_facet | Edlainny Araujo Ribeiro Ana Cristina Gales Ana Paula Streling de Oliveira Danilo Dias Coelho Rodrigo Alves de Oliveira Irmtraut Araci Hoffmann Pfrimer José Rodrigues do Carmo Filho |
| author_sort | Edlainny Araujo Ribeiro |
| collection | DOAJ |
| description | Abstract INTRODUCTION: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region. METHODS: The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE). RESULTS: Only 10 (55.6%) isolates harbored the gene bla OXA-23. PFGE analysis revealed that these isolates belong to a single clone. CONCLUSIONS: This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced. |
| first_indexed | 2024-04-12T14:29:09Z |
| format | Article |
| id | doaj.art-e1470e29498545ca969ecee8d924e32d |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-04-12T14:29:09Z |
| publishDate | 2020-11-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-e1470e29498545ca969ecee8d924e32d2022-12-22T03:29:21ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492020-11-015410.1590/0037-8682-0087-2020Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon regionEdlainny Araujo RibeiroAna Cristina GalesAna Paula Streling de OliveiraDanilo Dias CoelhoRodrigo Alves de OliveiraIrmtraut Araci Hoffmann PfrimerJosé Rodrigues do Carmo Filhohttps://orcid.org/0000-0002-5044-5724Abstract INTRODUCTION: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region. METHODS: The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE). RESULTS: Only 10 (55.6%) isolates harbored the gene bla OXA-23. PFGE analysis revealed that these isolates belong to a single clone. CONCLUSIONS: This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100602&tlng=enAcinetobacter baumanniiCarbapenem resistanceCarbapenemasebla OXA-23Gram-negative bacilli |
| spellingShingle | Edlainny Araujo Ribeiro Ana Cristina Gales Ana Paula Streling de Oliveira Danilo Dias Coelho Rodrigo Alves de Oliveira Irmtraut Araci Hoffmann Pfrimer José Rodrigues do Carmo Filho Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region Revista da Sociedade Brasileira de Medicina Tropical Acinetobacter baumannii Carbapenem resistance Carbapenemase bla OXA-23 Gram-negative bacilli |
| title | Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region |
| title_full | Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region |
| title_fullStr | Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region |
| title_full_unstemmed | Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region |
| title_short | Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region |
| title_sort | molecular epidemiology and drug resistance of acinetobacter baumannii isolated from a regional hospital in the brazilian amazon region |
| topic | Acinetobacter baumannii Carbapenem resistance Carbapenemase bla OXA-23 Gram-negative bacilli |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822021000100602&tlng=en |
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