The metazoan landscape of mitochondrial DNA gene order and content is shaped by selection and affects mitochondrial transcription

The analysis of mitochondrial DNA from over 8000 metazoans shows gene content conservation, association between preference for mtDNA-encoded tRNAs and codon usage, selective constraint for mtDNA rearrangements and their impact on mtDNA transcription.

Bibliographic Details
Main Authors: Noam Shtolz, Dan Mishmar
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04471-4

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