Modulation of the Primary Astrocyte-Enriched Cultures’ Oxylipin Profiles Reduces Neurotoxicity

Modulation of the Primary Astrocyte-Enriched Cultures’ Oxylipin Profiles Reduces Neurotoxicity

Recently, manipulations with reactive astrocytes have been viewed as a new therapeutic approach that will enable the development of treatments for acute brain injuries and neurodegenerative diseases. Astrocytes can release several substances, which may exert neurotoxic or neuroprotective effects, bu...

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Bibliographic Details
Main Authors: Mariia V. Guryleva, Dmitry V. Chistyakov, Alexander V. Lopachev, Sergei V. Goriainov, Alina A. Astakhova, Yulia A. Timoshina, Anastasiya V. Khutorova, Tatiana N. Fedorova, Marina G. Sergeeva
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Metabolites
Subjects:
astrocytes
neurons
ML355
Zileuton
lipoxygenases
interleukin 10 (IL-10)
Online Access:https://www.mdpi.com/2218-1989/11/8/498

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