EVALUACIÓN DE ALGUNOS FACTORES DE RIESGO DE CONTRAER HEPATITIS C EN PACIENTES HEMODIALIZADOS

The purpose of this study was to determine the prevalence of antibodies anti-VHC in three hemodialyzedgroups in Bogotá City, through searching of association of seroconversion which included three risksfactors: politrasfunded events, renal transplantion and treatment in different centers for hemodya...

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Bibliographic Details
Main Authors: A.R. Manascero-Gómez, M.F. Gutiérrez, C. Jaramillo-Tobón, L.S. Velásquez, J. Barrera
Format: Article
Language:English
Published: Pontificia Universidad Javeriana 2007-12-01
Series:Universitas Scientiarum
Subjects:
Online Access:https://docs.google.com/folder/d/0B_IdlsctkRrxVV8yVEVfRG1BQmM/edit?usp=sharing&pli=1&docId=0B_IdlsctkRrxOEpXSmhHUWMwRFk
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Summary:The purpose of this study was to determine the prevalence of antibodies anti-VHC in three hemodialyzedgroups in Bogotá City, through searching of association of seroconversion which included three risksfactors: politrasfunded events, renal transplantion and treatment in different centers for hemodyalisis.Presence of antibodies recognizing common epitopes of VHC were detected by ELISA test. As confirmationtest an immunoblot assay was performed and serotypes were determined by MUREX test, a non commercialELISA test. This type of study was descriptive and the risks factors were analyzed with the Fischer test.Prevalence of 2,7% was founded, mainly with serotype 1 (5/8 positive samples), 3 samples could not beserotyped using this technique.There was no association between risk factors and seropositivity. Even thought, prevalence was lowerthan expected. Predominant type 1 was predictable and risks factors did not show to have any relationshipwith seropositivity. Nosocomial transmission of VHC can not be excluded since it is one of the mostimportant ways to transmit the virus in this kind of patients.
ISSN:0122-7483
2027-1352