Hypomethylation of the LncRNA H19 promoter accelerates osteogenic differentiation of vascular smooth muscle cells by activating the Erk1/2 pathways
Objective Vascular calcification is a common chronic kidney disease complication. This study aimed to investigate the function of long non-coding RNA (LncRNA) H19 in vascular calcification to explore new therapeutic strategies. Methods We induced osteogenic differentiation and calcification of vascu...
Main Authors: | Taoxia Wang, Meijuan Cheng, Jingjing Jin, Yaling Bai, Dongxue Zhang, Shenglei Zhang, Jinsheng Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2024-03-01
|
Series: | Journal of International Medical Research |
Online Access: | https://doi.org/10.1177/03000605241234567 |
Similar Items
-
Extracellular acidosis suppresses calcification of vascular smooth muscle cells by inhibiting calcium influx via L-type calcium channels
by: Shenglei Zhang, et al.
Published: (2018-05-01) -
MiR-665 Regulates Vascular Smooth Muscle Cell Senescence by Interacting With LncRNA GAS5/SDC1
by: Tianbin Chen, et al.
Published: (2021-07-01) -
Clinicopathological Features of Anticancer Drug-induced Kidney Injury
by: GENG Tonghui, LI Han, JIN Jingjing, CHENG Meijuan, ZHANG Shenglei, BAI Yaling, XU Jinsheng
Published: (2022-11-01) -
The Role of Sirtuins in Osteogenic Differentiation of Vascular Smooth Muscle Cells and Vascular Calcification
by: Shuangshuang Wang, et al.
Published: (2022-06-01) -
Exosome-Derived LncRNA TCONS_00072128 Mediated Osteogenic Differentiation and Inflammation by Caspase 8 Regulation
by: Yongchang Yang, et al.
Published: (2022-03-01)