Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre
Background: The study assesses the impact of socio-demographic factors, including food habits and lifestyle factors, with their clinical outcome due to SARS-CoV-2 in a small tribal state in Northeast India. Methods: Clinical and demographic data from 896 patients with elevated levels of cytokine wer...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Clinical Epidemiology and Global Health |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213398424000927 |
| _version_ | 1797220298544644096 |
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| author | P.C. Lalrohlua Gracy Laldinmawii John Zohmingthanga Jane Ralte Lalengkimi Ralte John Zothanzama Nachimuthu.Senthil Kumar Swagnik Roy |
| author_facet | P.C. Lalrohlua Gracy Laldinmawii John Zohmingthanga Jane Ralte Lalengkimi Ralte John Zothanzama Nachimuthu.Senthil Kumar Swagnik Roy |
| author_sort | P.C. Lalrohlua |
| collection | DOAJ |
| description | Background: The study assesses the impact of socio-demographic factors, including food habits and lifestyle factors, with their clinical outcome due to SARS-CoV-2 in a small tribal state in Northeast India. Methods: Clinical and demographic data from 896 patients with elevated levels of cytokine were collected, retrospectively. The data was analyzed using IBM SPSSv.26 statistics to assess the correlation between the variables and the impact on patient's clinical outcomes. Results: The data consisted of 48.8% male and 51.2% female patients and the mean age was 30.73 years. The symptoms recorded during the hospital stay were anosmia followed by fever, cough, dysgeusia, hypertension, diabetes, diarrhoea, obesity, and shortness of breath. Comorbidities such as malnourishment, kidney diseases, cancers, and immune-compromised were found among them. Moreover, 67% were at risk of respiratory infection and the mean duration of hospital stay was 12–13 days. There was moderate consumption across all food types except for vegetables and smoked food and most patients didn't consume alcohol or smoke. A significant positive association was found both for respiratory infection (p = 0.001) and bad liver function (p = 0.045) with the duration of hospital stay. Individuals who do not consume gutkha (a blended areca nut with tobacco) tend to have lower ct-values (p = 0.011). Alcohol consumption was also significant with shortness of breath (p = 0.009), while smoking was significantly associated with anosmia (p = 0.044) and chest pain (p = 0.002). Conclusions: The demographic and health conditions were mostly not associated with the clinical outcome which could indicate that these practices might instead increase the recovery rate and in turn lower the death rates within the population. |
| first_indexed | 2024-04-24T12:47:19Z |
| format | Article |
| id | doaj.art-e1575b0996ce4157b53e7017a40fb6ee |
| institution | Directory Open Access Journal |
| issn | 2213-3984 |
| language | English |
| last_indexed | 2024-04-24T12:47:19Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Epidemiology and Global Health |
| spelling | doaj.art-e1575b0996ce4157b53e7017a40fb6ee2024-04-07T04:35:40ZengElsevierClinical Epidemiology and Global Health2213-39842024-05-0127101596Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centreP.C. Lalrohlua0Gracy Laldinmawii1John Zohmingthanga2Jane Ralte3Lalengkimi Ralte4John Zothanzama5Nachimuthu.Senthil Kumar6Swagnik Roy7Department of Biotechnology, Mizoram University (A Central University), Aizawl, 796004, Mizoram, IndiaDepartment of Microbiology, Zoram Medical College, Falkawn, 796005, Mizoram, IndiaZoram Medical College, Falkawn, 796005, Mizoram, IndiaZoram Medical College, Falkawn, 796005, Mizoram, IndiaDepartment of Biotechnology, Mizoram University (A Central University), Aizawl, 796004, Mizoram, IndiaDepartment of Biotechnology, Mizoram University (A Central University), Aizawl, 796004, Mizoram, IndiaDepartment of Biotechnology, Mizoram University (A Central University), Aizawl, 796004, Mizoram, IndiaDepartment of Microbiology, Zoram Medical College, Falkawn, 796005, Mizoram, India; Corresponding author.Background: The study assesses the impact of socio-demographic factors, including food habits and lifestyle factors, with their clinical outcome due to SARS-CoV-2 in a small tribal state in Northeast India. Methods: Clinical and demographic data from 896 patients with elevated levels of cytokine were collected, retrospectively. The data was analyzed using IBM SPSSv.26 statistics to assess the correlation between the variables and the impact on patient's clinical outcomes. Results: The data consisted of 48.8% male and 51.2% female patients and the mean age was 30.73 years. The symptoms recorded during the hospital stay were anosmia followed by fever, cough, dysgeusia, hypertension, diabetes, diarrhoea, obesity, and shortness of breath. Comorbidities such as malnourishment, kidney diseases, cancers, and immune-compromised were found among them. Moreover, 67% were at risk of respiratory infection and the mean duration of hospital stay was 12–13 days. There was moderate consumption across all food types except for vegetables and smoked food and most patients didn't consume alcohol or smoke. A significant positive association was found both for respiratory infection (p = 0.001) and bad liver function (p = 0.045) with the duration of hospital stay. Individuals who do not consume gutkha (a blended areca nut with tobacco) tend to have lower ct-values (p = 0.011). Alcohol consumption was also significant with shortness of breath (p = 0.009), while smoking was significantly associated with anosmia (p = 0.044) and chest pain (p = 0.002). Conclusions: The demographic and health conditions were mostly not associated with the clinical outcome which could indicate that these practices might instead increase the recovery rate and in turn lower the death rates within the population.http://www.sciencedirect.com/science/article/pii/S2213398424000927Clinical factorsMizoramSARS-CoV-2Socio-demographicsTertiary care center |
| spellingShingle | P.C. Lalrohlua Gracy Laldinmawii John Zohmingthanga Jane Ralte Lalengkimi Ralte John Zothanzama Nachimuthu.Senthil Kumar Swagnik Roy Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre Clinical Epidemiology and Global Health Clinical factors Mizoram SARS-CoV-2 Socio-demographics Tertiary care center |
| title | Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre |
| title_full | Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre |
| title_fullStr | Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre |
| title_full_unstemmed | Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre |
| title_short | Analysis of socio-demographic status and clinical manifestations among SARS-CoV-2 patients in ethnic tribal population of Mizoram, Northeast India: A retrospective study from single-tertiary COVID-19 care centre |
| title_sort | analysis of socio demographic status and clinical manifestations among sars cov 2 patients in ethnic tribal population of mizoram northeast india a retrospective study from single tertiary covid 19 care centre |
| topic | Clinical factors Mizoram SARS-CoV-2 Socio-demographics Tertiary care center |
| url | http://www.sciencedirect.com/science/article/pii/S2213398424000927 |
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