Immunoreactivity of p21, MMP-1 and CB2 receptor proteins in cutaneous canine mast cell tumours: an association with the three-tier grading system

Immunoreactivity of p21, MMP-1 and CB2 receptor proteins in cutaneous canine mast cell tumours: an association with the three-tier grading system

Mast cell tumours (MCTs) arise in the dermis and subcutaneous tissues in animals and humans and are one of the most common neoplasms of the skin in dogs. Cannabinoid type 2 receptor (CB2R), cyclin-dependent kinase inhibitor (p21) and matrix metalloproteinase 1 (MMP-1) are potential targets for novel...

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Bibliographic Details
Main Authors: Bulak Kamila, Kycko Anna, Śmiech Anna, Łopuszyński Wojciech
Format: Article
Language:English
Published: Sciendo 2023-12-01
Series:Journal of Veterinary Research
Subjects:
mast cell tumour
mmp-1 protein
p21 protein
cb2 receptor protein
cannabinoid
Online Access:https://doi.org/10.2478/jvetres-2023-0066

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