Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report

Seizure is the second most common neurologic complication after liver transplantation and may be caused by metabolic abnormalities, electrolyte imbalance, infection, and immunosuppressant toxicity. A 61-year-old male patient underwent liver transplantation due to hepatitis B virus-related liver cirr...

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Main Authors: Seung-Young Oh, Hannah Lee, Yang-Hyo Park, Ho Geol Ryu
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2016-10-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-69-527.pdf
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author Seung-Young Oh
Hannah Lee
Yang-Hyo Park
Ho Geol Ryu
author_facet Seung-Young Oh
Hannah Lee
Yang-Hyo Park
Ho Geol Ryu
author_sort Seung-Young Oh
collection DOAJ
description Seizure is the second most common neurologic complication after liver transplantation and may be caused by metabolic abnormalities, electrolyte imbalance, infection, and immunosuppressant toxicity. A 61-year-old male patient underwent liver transplantation due to hepatitis B virus-related liver cirrhosis with portal systemic encephalopathy. The immediate postoperative course of the patient was uncomplicated. However, on postoperative day (POD) 6, weakness developed in both lower extremities. No abnormal findings were detected on a brain computed tomography (CT) scan on POD 8, but a generalized tonic clonic seizure developed which was difficult to control even with multiple antiepileptic drugs. A follow-up brain CT scan on POD 15 showed a 2.7 cm sized acute intracranial hemorrhage (ICH) in the left parietal lobe. The patient's mental status improved after 2 months and he was able to communicate through eye blinking or head shaking. Our case reports an acute ICH that manifested into a refractory seizure in a patient who underwent a liver transplant.
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spelling doaj.art-e15d4c02b39b411b821663fa255514432022-12-21T17:45:50ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632016-10-0169552753110.4097/kjae.2016.69.5.5278231Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case reportSeung-Young Oh0Hannah Lee1Yang-Hyo Park2Ho Geol Ryu3Department of Surgery, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Department of Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea.Seizure is the second most common neurologic complication after liver transplantation and may be caused by metabolic abnormalities, electrolyte imbalance, infection, and immunosuppressant toxicity. A 61-year-old male patient underwent liver transplantation due to hepatitis B virus-related liver cirrhosis with portal systemic encephalopathy. The immediate postoperative course of the patient was uncomplicated. However, on postoperative day (POD) 6, weakness developed in both lower extremities. No abnormal findings were detected on a brain computed tomography (CT) scan on POD 8, but a generalized tonic clonic seizure developed which was difficult to control even with multiple antiepileptic drugs. A follow-up brain CT scan on POD 15 showed a 2.7 cm sized acute intracranial hemorrhage (ICH) in the left parietal lobe. The patient's mental status improved after 2 months and he was able to communicate through eye blinking or head shaking. Our case reports an acute ICH that manifested into a refractory seizure in a patient who underwent a liver transplant.http://ekja.org/upload/pdf/kjae-69-527.pdfencephalopathyintracranial hemorrhagesliver transplantationseizures
spellingShingle Seung-Young Oh
Hannah Lee
Yang-Hyo Park
Ho Geol Ryu
Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
Korean Journal of Anesthesiology
encephalopathy
intracranial hemorrhages
liver transplantation
seizures
title Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
title_full Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
title_fullStr Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
title_full_unstemmed Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
title_short Intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient: a case report
title_sort intracranial hemorrhage induced uncontrolled seizure in a deceased donor liver transplant patient a case report
topic encephalopathy
intracranial hemorrhages
liver transplantation
seizures
url http://ekja.org/upload/pdf/kjae-69-527.pdf
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AT yanghyopark intracranialhemorrhageinduceduncontrolledseizureinadeceaseddonorlivertransplantpatientacasereport
AT hogeolryu intracranialhemorrhageinduceduncontrolledseizureinadeceaseddonorlivertransplantpatientacasereport