Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden
OBJECTIVE: To study some hematological parameters in adult patients with complicated severe malaria and their relations to clinical outcome. METHODS: This was a prospective study, including 77 patients from Aden Governorate with complicated severe malaria over the course of 2 years (2010-2011). RESU...
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Format: | Article |
Language: | English |
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Galenos Publishing House
2013-12-01
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Series: | Turkish Journal of Hematology |
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Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-49092 |
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author | Sawsan Bakhubaira |
author_facet | Sawsan Bakhubaira |
author_sort | Sawsan Bakhubaira |
collection | DOAJ |
description | OBJECTIVE: To study some hematological parameters in adult patients with complicated severe malaria and their relations to clinical outcome. METHODS: This was a prospective study, including 77 patients from Aden Governorate with complicated severe malaria over the course of 2 years (2010-2011). RESULTS: The common form of severe malaria in Aden was cerebral malaria (25.9%), followed by renal failure (18.2%), severe anemia (16.9%), and hepatitis (14.3%), with a case fatality rate of 7.8%. Hemoglobin concentration was significantly different among the various complications of severe malaria, while platelet and white blood cell counts did not show such differences. The mean age was older among patients that died. Hematological parameters did not significantly differ among dead or surviving patients. Thrombocytopenia was seen in 42.9% of patients and 18.2% of these had platelet counts of <50.0x109/L. However, none of them developed bleeding. CONCLUSION: This study concluded that hematological changes are common complications encountered in severe malaria, but they are not related to the clinical outcome. |
first_indexed | 2024-04-10T14:22:21Z |
format | Article |
id | doaj.art-e15f459515f44295a144ec80785adf48 |
institution | Directory Open Access Journal |
issn | 1308-5263 |
language | English |
last_indexed | 2024-04-10T14:22:21Z |
publishDate | 2013-12-01 |
publisher | Galenos Publishing House |
record_format | Article |
series | Turkish Journal of Hematology |
spelling | doaj.art-e15f459515f44295a144ec80785adf482023-02-15T16:09:16ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632013-12-0130439439910.4274/Tjh.2012.0086TJH-49092Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in AdenSawsan Bakhubaira0Aden University, Faculty Of Medicine And Health Sciences, Department Of Hematology Oncology, Aden, YemenOBJECTIVE: To study some hematological parameters in adult patients with complicated severe malaria and their relations to clinical outcome. METHODS: This was a prospective study, including 77 patients from Aden Governorate with complicated severe malaria over the course of 2 years (2010-2011). RESULTS: The common form of severe malaria in Aden was cerebral malaria (25.9%), followed by renal failure (18.2%), severe anemia (16.9%), and hepatitis (14.3%), with a case fatality rate of 7.8%. Hemoglobin concentration was significantly different among the various complications of severe malaria, while platelet and white blood cell counts did not show such differences. The mean age was older among patients that died. Hematological parameters did not significantly differ among dead or surviving patients. Thrombocytopenia was seen in 42.9% of patients and 18.2% of these had platelet counts of <50.0x109/L. However, none of them developed bleeding. CONCLUSION: This study concluded that hematological changes are common complications encountered in severe malaria, but they are not related to the clinical outcome.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-49092complicatedseveremalariathrombocytopenia |
spellingShingle | Sawsan Bakhubaira Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden Turkish Journal of Hematology complicated severe malaria thrombocytopenia |
title | Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden |
title_full | Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden |
title_fullStr | Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden |
title_full_unstemmed | Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden |
title_short | Hematological Parameters in Severe Complicated Plasmodium falciparum Malaria among Adults in Aden |
title_sort | hematological parameters in severe complicated plasmodium falciparum malaria among adults in aden |
topic | complicated severe malaria thrombocytopenia |
url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-49092 |
work_keys_str_mv | AT sawsanbakhubaira hematologicalparametersinseverecomplicatedplasmodiumfalciparummalariaamongadultsinaden |