Raman spectroscopy and mass spectrometry identifies a unique group of epidermal lipids in active discoid lupus erythematosus

Abstract Discoid lupus erythematosus (DLE) is the most common form of cutaneous lupus1. It can cause permanent scarring. The pathophysiology of is not fully understood. Plasmacytoid dendritic cells are found in close association with apoptotic keratinocytes inferring close cellular signalling. Matri...

Full description

Bibliographic Details
Main Authors: Hannah U Holtkamp, Claude Aguergaray, Kalita Prangnell, Christopher Pook, Satya Amirapu, Angus Grey, Cather Simpson, Michel Nieuwoudt, Paul Jarrett
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43331-3